Gene Symbol | BATF2 |
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Entrez Gene | 116071 |
Alt Symbol | SARI |
Species | Human |
Gene Type | protein-coding |
Description | basic leucine zipper transcription factor, ATF-like 2 |
Other Description | B-ATF-2|basic leucine zipper transcriptional factor ATF-like 2|suppressor of AP-1 regulated by IFN |
Swissprots | D9IC56 Q8N1L9 Q96EH4 Q8NAF4 Q8NAL8 |
Accessions | EAW74330 EAW74331 Q8N1L9 AK092453 BAC03894 AK096702 BAC04846 AK300917 BAG62549 BC011931 BC012330 AAH12330 BP206576 HM134154 ADJ55304 XM_011544750 XP_011543052 NM_001300807 NP_001287736 NM_001300808 NP_001287737 NM_138456 NP_612465 |
Function | AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter. {ECO:0000250, ECO:0000269|PubMed:20531301}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}. |
Human MGC20410 full length protein - ab165091 from Abcam
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BATF2 / SARI Antibody Blocking Peptide - LS-E5090 from LifeSpan Bioscience
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BATF2 / SARI Antibody Blocking Peptide - LS-E17307 from LifeSpan Bioscience
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Recombinant Human MGC20410 Protein - H00116071-P01 from Novus Biologicals
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BATF2-Antibody-N-term-Blocking-Peptide - BP17506a from Abgent, a WuXi AppTec company
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BATF2 Blocking Peptide - 33R-6095 from Fitzgerald
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BATF2 Blocking Peptide - 33R-1457 from Fitzgerald
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BATF2 Blocking Peptide - abx064038 from Abbexa
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BATF2 - H00116071-P01-10 from Acris Antibodies
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BATF2 - H00116071-P01-25 from Acris Antibodies
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BATF2 fusion protein - ag9551 from Proteintech Group
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BATF2 Blocking Peptide - CBP2844 from Cohesion Biosciences
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Recombinant Human Basic leucine zipper transcriptional factor ATF-like 2(BATF2) - CSB-YP822685HU CSB-EP822685HU CSB-BP822685HU CSB-MP822685HU from Cusabio
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BATF2 (N-term HIS tag) - TP760348 from Acris Antibodies
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MGC20410 Recombinant Protein Antigen - NBP2-38963PEP from Novus Biologicals
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BATF2 Peptide, Human - M34GP01330H from Creative Peptides
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Basic leucine zipper transcriptional factor ATF-like 2 (BATF2), Recombinant Protein - MBS1427363 from MyBioSource
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Recombinant Human BATF2 Protein, His-tagged - BATF2-2373H from Creative Biomart
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Recombinant Human BATF2 Protein, GST-tagged - BATF2-4344H from Creative Biomart
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