DLC1

Gene Symbol	DLC1
Entrez Gene	10395
Alt Symbol	ARHGAP7, HP, STARD12, p122-RhoGAP
Species	Human
Gene Type	protein-coding
Description	DLC1 Rho GTPase activating protein
Other Description	Rho-GTPase-activating protein 7|START domain-containing protein 12|StAR-related lipid transfer (START) domain containing 12|deleted in liver cancer 1 protein|deleted in liver cancer 1 variant 2|rho GTPase-activating protein 7|rho-type GTPase-activating protein 7
Swissprots	Q9H7A2 O14868 Q9C0E0 E9PGY9 B8PTI0 Q7Z5R8 B4DR10 Q96QB1 E9PF76 Q86UC6 E9PDZ8 O43199
Accessions	AAK97501 EAW63851 EAW63852 EAW63853 EAW63854 EAW63855 Q96QB1 AB051510 BAB21814 AF026219 AAB81637 AF035119 AAB87700 AK023128 AK024773 BAB14996 AK025544 AK025733 AK225098 AK289734 BAF82423 AK291682 BAF84371 AK299049 BAG61122 AL117604 BC049842 AAH49842 BC054511 AAH54511 BC095415 BP284911 CB961755 DA549448 DQ092382 AAZ32940 DQ092383 AAZ32941 DQ092384 AAZ32942 EU832131 ACE87481 EU832224 ACE86794 XM_005273374 XP_005273431 XM_005273375 XP_005273432 NM_001164271 NP_001157743 NM_006094 NP_006085 NM_024767 NP_079043 NM_182643 NP_872584
Function	Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. {ECO:0000269|PubMed:18786931, ECO:0000269|PubMed:19170769, ECO:0000269|PubMed:19710422}.
Subcellular Location	Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Note=Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
Tissue Specificity	Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DLC1 (Human) IP-WB Antibody Pair - H00010395-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

deleted in liver cancer 1, ELISA Kit - MBS9330135 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.25ng/ml-8ng/ml.

ELISA Kit for Deleted In Liver Cancer 1 (DLC1) - SEG500Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

DLC1 ELISA Kit (Human) (OKCD01918) - OKCD01918 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.063 ng/mL Range 0.156 - 10 ng/mL

Human Deleted In Liver Cancer 1 (DLC1) ELISA Kit - AE47172HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.063 ng/mL Range 0.156-10 ng/mL

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9345122 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9369294 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9360629 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9358766 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9345619 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9354586 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9358281 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9353832 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9362055 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9363989 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9353536 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9347120 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9365671 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9357213 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Deleted In Liver Cancer 1, ELISA Kit - MBS2031914 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.063ng/mL. Range 0.156-10ng/mL. The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.312ng/mL, 0.156ng/mL.

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9355919 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9360986 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9369621 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9348597 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Rho GTPase-Activating Protein 7 (DLC1), ELISA Kit - MBS9367860 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more