RDH11

Gene Symbol	RDH11
Entrez Gene	51109
Alt Symbol	ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, RDJCSS, SCALD, SDR7C1
Species	Human
Gene Type	protein-coding
Description	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
Other Description	HCV core-binding protein HCBP12|androgen-regulated short-chain dehydrogenase/reductase 1|prostate short-chain dehydrogenase reductase 1|prostate short-chain dehydrogenase/reductase 1|retinal reductase 1|retinol dehydrogenase 11|short chain dehydrogenase/reductase family 7C member 1|short chain dehydrogenase/reductase family 7C, member 1
Swissprots	Q0QD40 Q9Y391 Q6IAH5 B4DDW0 A6NDK3 A8K062 B2RB26 Q8TC12 Q9NRW0
Accessions	CAF86792 EAW80948 EAW80949 EAW80950 Q8TC12 AB209223 BAD92460 AF151840 AAD34077 AF167438 AAF89632 AF395068 AAK72049 AI382141 AK057195 BAG51881 AK074749 BAG51997 AK289427 BAF82116 AK293355 BAG56871 AK307500 AK314465 BAG37073 BC000112 AAH00112 BC011727 AAH11727 BC026274 AAH26274 BC037302 AAH37302 BC051291 AAH51291 CR457180 CAG33461 DC355364 DQ426886 ABD90542 HQ447163 ADQ31650 NM_001252650 NP_001239579 NM_016026 NP_057110
Function	Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:12036956}; Single-pass type II membrane protein {ECO:0000269|PubMed:12036956}.
Tissue Specificity	Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.
Top Pathways	Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-RDH11-cDNA-Clone - DC07139 from Abgent, a WuXi AppTec company Prices $429.30 Sizes 10 µg Species Human Accession BC011727

RDH11 - MBS1275992 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC026274

RDH11 - MBS1274250 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC037302

RDH11 - MBS1267939 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC011727

Human RDH11 Gene cDNA clone plasmid - HG14102-G from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid - HG14102-UT from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14102-ACR from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14102-CY from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14102-ANR from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14102-ACG from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, N-His tag - HG14102-NH from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14102-NF from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14102-NM from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14102-CF from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14102-CM from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, C-His tag - HG14102-CH from Sino Biological Species Human

Human RDH11 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14102-NY from Sino Biological Species Human

Human RDH11 natural ORF mammalian expression plasmid, N-GFPSpark tag - HG14102-ANG from Sino Biological Species Human Accession BC011727

human RDH11 ORF clone (NM_001252650.1) - CDCH072690 from Creative biogene Species Human

Human RDH11 ORF Clone (BC011727) - CDCS409978 from Creative biogene Species Human Accession Q8TC12

Human RDH11 ORF Clone (BC037302) - CDCS409979 from Creative biogene Species Human Accession Q8TC12

Human RDH11 ORF Clone (BC026274) - CDCS409980 from Creative biogene Species Human Accession Q8TC12

Human RDH11 ORF clone (BC011727) - CDCB159386 from Creative biogene Species Human

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