RDH11

Gene Symbol RDH11
Entrez Gene 51109
Alt Symbol ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, RDJCSS, SCALD, SDR7C1
Species Human
Gene Type protein-coding
Description retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
Other Description HCV core-binding protein HCBP12|androgen-regulated short-chain dehydrogenase/reductase 1|prostate short-chain dehydrogenase reductase 1|prostate short-chain dehydrogenase/reductase 1|retinal reductase 1|retinol dehydrogenase 11|short chain dehydrogenase/reductase family 7C member 1|short chain dehydrogenase/reductase family 7C, member 1
Swissprots Q0QD40 Q9Y391 Q6IAH5 B4DDW0 A6NDK3 A8K062 B2RB26 Q8TC12 Q9NRW0
Accessions CAF86792 EAW80948 EAW80949 EAW80950 Q8TC12 AB209223 BAD92460 AF151840 AAD34077 AF167438 AAF89632 AF395068 AAK72049 AI382141 AK057195 BAG51881 AK074749 BAG51997 AK289427 BAF82116 AK293355 BAG56871 AK307500 AK314465 BAG37073 BC000112 AAH00112 BC011727 AAH11727 BC026274 AAH26274 BC037302 AAH37302 BC051291 AAH51291 CR457180 CAG33461 DC355364 DQ426886 ABD90542 HQ447163 ADQ31650 NM_001252650 NP_001239579 NM_016026 NP_057110
Function Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12036956}; Single-pass type II membrane protein {ECO:0000269|PubMed:12036956}.
Tissue Specificity Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.
Top Pathways Retinol metabolism

RDH11 (A-18) - sc-51419 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RDH11 (D-14) - sc-51420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RDH11 (D-14): sc-51420. Western blot analysis of RDH11 expression in PC-3 whole cell lysate.

RDH11 (F-1) - sc-514370 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RDH11 (F-1): sc-514370. Western blot analysis of RDH11 expression in LNCaP (A), Hep G2 (B) and Hs 181 Tes (C) whole cell lysates.

RDH11 (EE-12) - sc-100588 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
RDH11 (EE-12): sc-100588. Western blot analysis of RDH11 expression in HeLa whole cell lysate.

RDH11 (H-43) - sc-366397 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-RDH11 antibody - ab85849 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Formalin fixed and paraffin embedded human kidney tissue labelled with ab85849 at 5 µg/ml.

Anti-RDH11 antibody - ab1404 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 antibody - ab57380 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-RDH11 Antibody (clone 1B4) - LS-C115095 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B4
IHC of paraffin-embedded pancreas tissue using anti-RDH11 mouse monoclonal antibody. (Dilution 1:50).

Anti-RDH11 Antibody (N-Terminus) IHC-plus™ - LS-B2363 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RDH11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2363 concentration 5 ug/ml.

Anti-RDH11 Antibody (N-Terminus) - LS-C38648 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (C-Terminus) - LS-C46836 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (N-Terminus) - LS-C53362 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (C-Terminus) - LS-C53404 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (N-Terminus) - LS-C83448 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (N-Terminus) - LS-C91631 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (FITC) - LS-C318172 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody - LS-C318171 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (HRP) - LS-C318173 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (aa24-319, Azide-free) - LS-C328509 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RDH11 Antibody (Biotin) - LS-C318174 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RDH11 Antibody (C-Terminus) - LS-C81221 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

RDH11 Antibody (1B4) - NBP2-02431 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B4

RDH11 Antibody - NBP2-27584 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RDH11 Antibody [NBP2-27584] - WB detection of human RDH11 in androgen stimulated metastatic adenocarcinoma LNCaP.FGC cells with NBP2-27584 at a dilution of 1:500

RDH11 Antibody - NBP1-57976 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
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