RDH11

Gene Symbol RDH11
Entrez Gene 51109
Alt Symbol ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, RDJCSS, SCALD, SDR7C1
Species Human
Gene Type protein-coding
Description retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
Other Description HCV core-binding protein HCBP12|androgen-regulated short-chain dehydrogenase/reductase 1|prostate short-chain dehydrogenase reductase 1|prostate short-chain dehydrogenase/reductase 1|retinal reductase 1|retinol dehydrogenase 11|short chain dehydrogenase/reductase family 7C member 1|short chain dehydrogenase/reductase family 7C, member 1
Swissprots Q0QD40 Q9Y391 Q6IAH5 B4DDW0 A6NDK3 A8K062 B2RB26 Q8TC12 Q9NRW0
Accessions CAF86792 EAW80948 EAW80949 EAW80950 Q8TC12 AB209223 BAD92460 AF151840 AAD34077 AF167438 AAF89632 AF395068 AAK72049 AI382141 AK057195 BAG51881 AK074749 BAG51997 AK289427 BAF82116 AK293355 BAG56871 AK307500 AK314465 BAG37073 BC000112 AAH00112 BC011727 AAH11727 BC026274 AAH26274 BC037302 AAH37302 BC051291 AAH51291 CR457180 CAG33461 DC355364 DQ426886 ABD90542 HQ447163 ADQ31650 NM_001252650 NP_001239579 NM_016026 NP_057110
Function Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:12036956}; Single-pass type II membrane protein {ECO:0000269|PubMed:12036956}.
Tissue Specificity Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes.
Top Pathways Retinol metabolism

RDH11 CRISPR/Cas9 KO Plasmid (h) - sc-408065 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 HDR Plasmid (h) - sc-408065-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 Double Nickase Plasmid (h) - sc-408065-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 Double Nickase Plasmid (h2) - sc-408065-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 CRISPR Activation Plasmid (h) - sc-408065-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 CRISPR Activation Plasmid (h2) - sc-408065-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 Lentiviral Activation Particles (h) - sc-408065-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 Lentiviral Activation Particles (h2) - sc-408065-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH11 siRNA (h) - sc-72264 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH11 shRNA Plasmid (h) - sc-72264-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH11 shRNA (h) Lentiviral Particles - sc-72264-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH11 RNAi - H00051109-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU040931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18111 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18111 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09568 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09568

RDH11 siRNA (Human) - CRH9530 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RDH11 - MBS8200187 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RDH11 (NM_016026.3) - SHH391452 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human RDH11(NM_016026.3) - SHR174206 from Creative biogene

Category siRNA
Species Reactivities Human

RDH11 shRNA Plasmid (Human) - CHH9530 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RDH11 miRNA 3'UTR clone - MiUTR1H-08718 from Creative biogene

Species Reactivities Human
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