Gene Symbol | ITGAX |
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Entrez Gene | 3687 |
Alt Symbol | CD11C, SLEB6 |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha X (complement component 3 receptor 4 subunit) |
Other Description | CD11 antigen-like family member C|integrin alpha-X|integrin, alpha X (antigen CD11C (p150), alpha polypeptide)|leu M5, alpha subunit|leukocyte adhesion glycoprotein p150,95 alpha chain|leukocyte adhesion receptor p150,95|leukocyte surface antigen p150,95, alpha subunit|myeloid membrane antigen, alpha subunit|p150 95 integrin alpha chain |
Swissprots | Q8IVA6 P20702 |
Accessions | AAA35661 AAA51620 EAW52140 EAW52141 EAW52142 P20702 AK074047 BAB84873 AK293367 BAG56881 AK296666 BAG59263 AK309642 AW014280 BC037577 BC038237 AAH38237 BM149283 CA308944 DA324567 DQ892486 ABM83412 DQ895697 ABM86623 M81695 AAA59180 XM_011545852 XP_011544154 XM_011545853 XP_011544155 XM_011545854 XP_011544156 XR_950797 NM_000887 NP_000878 NM_001286375 NP_001273304 |
Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
Top Pathways | Tuberculosis, Regulation of actin cytoskeleton |
Integrin αX (B-6) - sc-46676 from Santa Cruz Biotechnology
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Integrin αX (BU15) - sc-19618 from Santa Cruz Biotechnology
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Integrin αX (G-3) - sc-398725 from Santa Cruz Biotechnology
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Integrin αX (KB90) - sc-20051 from Santa Cruz Biotechnology
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Integrin αX (3.9) - sc-1185 from Santa Cruz Biotechnology
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Integrin αX (B-Iy6) - sc-19989 from Santa Cruz Biotechnology
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Integrin αX (HC1/1) - sc-53998 from Santa Cruz Biotechnology
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Integrin αX (2Q862) - sc-71454 from Santa Cruz Biotechnology
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Integrin αX (2B2.36) - sc-71453 from Santa Cruz Biotechnology
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Integrin αX (2Q865) - sc-71455 from Santa Cruz Biotechnology
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Integrin αX (H-68) - sc-28663 from Santa Cruz Biotechnology
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Integrin αX (N-19) - sc-6620 from Santa Cruz Biotechnology
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Integrin αX (C-20) - sc-6619 from Santa Cruz Biotechnology
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Anti-CD11c [HC1/1] antibody - ab191540 from Abcam
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Anti-CD11c antibody - ab196354 from Abcam
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Anti-CD11c antibody - ab82508 from Abcam
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Anti-CD11c antibody - ab96711 from Abcam
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Anti-CD11c antibody [3.9] - ab11029 from Abcam
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Anti-CD11c antibody [3.9] (Allophycocyanin) - ab95764 from Abcam
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Anti-CD11c antibody [3.9] (Biotin) - ab19682 from Abcam
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Anti-CD11c antibody [3.9] (FITC) - ab82445 from Abcam
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Anti-CD11c antibody [3.9] (Phycoerythrin) - ab82440 from Abcam
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Anti-CD11c antibody [3.9], prediluted (PE/Cy7 ®) - ab155349 from Abcam
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Anti-CD11c antibody [BU15] - ab23506 from Abcam
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Anti-CD11c antibody [BU15] - ab76911 from Abcam
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