Gene Symbol | TIMM13 |
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Entrez Gene | 26517 |
Alt Symbol | TIM13, TIM13B, TIMM13A, TIMM13B, ppv1 |
Species | Human |
Gene Type | protein-coding |
Description | translocase of inner mitochondrial membrane 13 homolog (yeast) |
Other Description | mitochondrial import inner membrane translocase subunit Tim13|mitochondrial import inner membrane translocase subunit Tim13B |
Swissprots | Q9Y5L4 P62206 |
Accessions | EAW69380 EAW69381 Q9Y5L4 AF144700 AAD39951 AF152352 AAF15102 AK024764 AL520160 BC008607 AAH08607 BI908100 BI966836 BQ015233 DA890574 DA947460 DQ891755 ABM82681 DQ894937 ABM85863 NM_012458 NP_036590 |
Function | Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. {ECO:0000269|PubMed:11489896, ECO:0000269|PubMed:15254020}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:11489896}; Peripheral membrane protein {ECO:0000269|PubMed:11489896}; Intermembrane side {ECO:0000269|PubMed:11489896}. |
Tissue Specificity | Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. |
Tim13A/B (C-20) - sc-17065 from Santa Cruz Biotechnology
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Anti-TIMM13 antibody - ab66142 from Abcam
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Anti-TIMM13 Antibody (N-Terminus) - LS-C135327 from LifeSpan Bioscience
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TIMM13 Antibody - NBP2-13431 from Novus Biologicals
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TIMM13 Antibody (4F4) - H00026517-M03A from Novus Biologicals
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TIMM13 Antibody - H00026517-A01 from Novus Biologicals
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Anti-TIMM13 antibody produced in rabbit - HPA048985 from Sigma-Aldrich
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Monoclonal Anti-TIMM13 antibody produced in mouse - SAB1403187 from Sigma-Aldrich
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TIMM13 antibody - 70R-20827 from Fitzgerald
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TIMM13 antibody - 11973-1-AP from Acris Antibodies
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TIMM13 antibody - H00026517-A01 from Acris Antibodies
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TIMM13 antibody - H00026517-M03A from Acris Antibodies
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Mouse Anti-Human TIMM13 - 101-11780 from RayBiotech
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TIMM13 antibody - 11973-1-AP from Proteintech Group
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TIMM13, Monoclonal Antibody - MBS641356 from MyBioSource
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Anti-TIMM13 monoclonal antibody - DCABH-13765 from Creative Diagnostics
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Anti-translocase of inner mitochondrial membrane 13 homolog (yeast) - 08A026517 from MP Biomedicals
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TIMM13 Antibody - SH-A16290 from Novatein Biosciences
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Anti-TIMM13 monoclonal antibody, clone 5G5 - CABT-BL5852 from Creative Diagnostics
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Anti-TIMM13 (full length) polyclonal antibody - CABT-BL5850 from Creative Diagnostics
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anti-TIMM13 antibody - A008696 from Biobool
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TIMM13 Polyclonal Antibody - A13913 from ABclonal
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Anti-TIMM13 Antibody - LS-C661040 from LifeSpan Bioscience
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Anti-TIMM13 Antibody (N-Terminus, Biotin) - LS-C459321 from LifeSpan Bioscience
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Anti-TIMM13 Antibody (N-Terminus, HRP) - LS-C459323 from LifeSpan Bioscience
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