Gene Symbol | TIMM13 |
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Entrez Gene | 26517 |
Alt Symbol | TIM13, TIM13B, TIMM13A, TIMM13B, ppv1 |
Species | Human |
Gene Type | protein-coding |
Description | translocase of inner mitochondrial membrane 13 homolog (yeast) |
Other Description | mitochondrial import inner membrane translocase subunit Tim13|mitochondrial import inner membrane translocase subunit Tim13B |
Swissprots | Q9Y5L4 P62206 |
Accessions | EAW69380 EAW69381 Q9Y5L4 AF144700 AAD39951 AF152352 AAF15102 AK024764 AL520160 BC008607 AAH08607 BI908100 BI966836 BQ015233 DA890574 DA947460 DQ891755 ABM82681 DQ894937 ABM85863 NM_012458 NP_036590 |
Function | Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. {ECO:0000269|PubMed:11489896, ECO:0000269|PubMed:15254020}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:11489896}; Peripheral membrane protein {ECO:0000269|PubMed:11489896}; Intermembrane side {ECO:0000269|PubMed:11489896}. |
Tissue Specificity | Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. |
Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), Human, ELISA Kit - E01M0102 from ARP American Research Products
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7217680 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7216153 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7211546 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7207716 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7201378 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7220869 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7217841 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7233723 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7248849 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7204596 from MyBioSource
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Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13), ELISA Kit - MBS7230710 from MyBioSource
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Human TIMM13 ELISA Kit - E024624 from Biobool
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