KCNJ8

Gene Symbol KCNJ8
Entrez Gene 3764
Alt Symbol KIR6.1, uKATP-1
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 8
Other Description ATP-sensitive inward rectifier potassium channel 8|inward rectifier K(+) channel Kir6.1|inwardly rectifying potassium channel KIR6.1|potassium channel, inwardly rectifying subfamily J member 8|potassium inwardly-rectifying channel, subfamily J, member 8
Swissprots O00657 Q15842
Accessions BAA08852 EAW96450 EAW96451 Q15842 AK291821 BAF84510 AL546327 BC000544 AAH00544 BQ003792 BQ009215 D50312 BAA08851 DQ891913 ABM82839 DQ895097 ABM86023 XM_005253358 XP_005253415 NM_004982 NP_004973
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Predominantly detected in fetal and adult heart. {ECO:0000269|PubMed:9573340}.
Top Pathways cGMP-PKG signaling pathway

KCNJ8 / Kir6.1 Antibody Blocking Peptide - LS-E1563 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KCNJ8 / Kir6.1 Antibody Blocking Peptide - LS-E12509 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KCNJ8-Antibody-N-term-Blocking-peptide - BP12302a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KCNJ8 Blocking Peptide - 33R-2518 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

KCNJ8 fusion protein - Ag6792 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

KCNJ8 fusion protein - ag6880 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human KCNJ8, GST-tagged - KCNJ8-260H from Creative Biomart

Category Protein
Source E.coli
Species Human

KIR6.1 (345-424) - sc-4517 WB from Santa Cruz Biotechnology

Category Protein
Prices $88.00
Sizes 10 µg/0.1 ml
Species Human

Kir6.1 Recombinant Protein Antigen - NBP1-87710PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

KCNJ8 Peptide, Human - M34GP07973H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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