KCNJ8

Gene Symbol KCNJ8
Entrez Gene 3764
Alt Symbol KIR6.1, uKATP-1
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 8
Other Description ATP-sensitive inward rectifier potassium channel 8|inward rectifier K(+) channel Kir6.1|inwardly rectifying potassium channel KIR6.1|potassium channel, inwardly rectifying subfamily J member 8|potassium inwardly-rectifying channel, subfamily J, member 8
Swissprots O00657 Q15842
Accessions BAA08852 EAW96450 EAW96451 Q15842 AK291821 BAF84510 AL546327 BC000544 AAH00544 BQ003792 BQ009215 D50312 BAA08851 DQ891913 ABM82839 DQ895097 ABM86023 XM_005253358 XP_005253415 NM_004982 NP_004973
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Predominantly detected in fetal and adult heart. {ECO:0000269|PubMed:9573340}.
Top Pathways cGMP-PKG signaling pathway

KIR6.1 CRISPR/Cas9 KO Plasmid (h) - sc-401477 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 HDR Plasmid (h) - sc-401477-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 Double Nickase Plasmid (h) - sc-401477-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 Double Nickase Plasmid (h2) - sc-401477-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 CRISPR Activation Plasmid (h) - sc-401477-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 CRISPR Activation Plasmid (h2) - sc-401477-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 Lentiviral Activation Particles (h) - sc-401477-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 Lentiviral Activation Particles (h2) - sc-401477-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 siRNA (h) - sc-35752 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIR6.1 shRNA Plasmid (h) - sc-35752-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIR6.1 shRNA (h) Lentiviral Particles - sc-35752-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU027811 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10960 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10960 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06397 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06397

KCNJ8 siRNA (Human) - CRH2540 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Kir6.1 RNAi - H00003764-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KIR6.1 CRISPR/Cas9 KO Plasmid (h2) - sc-401477-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIR6.1 HDR Plasmid (h2) - sc-401477-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human KCNJ8 (NM_004982.3) - SHH323335 from Creative biogene

Category siRNA
Species Reactivities Human

Human KCNJ8 siRNA - orb263042 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNJ8 shRNA Plasmid (Human) - CHH2540 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNJ8 miRNA 3'UTR clone - MiUTR3H-03748 from Creative biogene

Species Reactivities Human
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