TRIM22

Gene Symbol TRIM22
Entrez Gene 10346
Alt Symbol GPSTAF50, RNF94, STAF50
Species Human
Gene Type protein-coding
Description tripartite motif containing 22
Other Description 50 kDa-stimulated trans-acting factor|E3 ubiquitin-protein ligase TRIM22|RING finger protein 94|staf-50|stimulated trans-acting factor (50 kDa)|tripartite binding motif 22|tripartite motif protein TRIM22|tripartite motif-containing 22|tripartite motif-containing protein 22
Swissprots Q8IYM9 Q05CQ0 Q15521
Accessions EAW68767 EAW68768 EAW68769 EAW68770 Q8IYM9 AK290434 BAF83123 AK298715 BAG60871 AK298934 BAG61037 AK301192 BAG62772 AK308221 AK308796 AK310098 AK311659 AL360134 AL360187 AL360190 AM040752 CAJ13842 BC022281 AAH22281 BC035582 AAH35582 CD621768 DC364428 DQ891201 ABM82127 DQ894384 ABM85310 HQ842635 ADY69767 X82200 CAA57684 NM_001199573 NP_001186502 NM_006074 NP_006065
Function Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity. {ECO:0000269|PubMed:18389079, ECO:0000269|PubMed:18656448, ECO:0000269|PubMed:19218198, ECO:0000269|PubMed:19585648}.
Subcellular Location Cytoplasm. Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Localizes predominanltly into the nucleus, found in cytoplasm to some extent. Forms distinct nuclear bodies that undergo dynamic changes during cell cycle progression. Nuclear bodies start to form in the early G0/G1 phase but become speckle-like in the S-phase and completely dispersed in mitosis. 35% of TRIM22 nuclear bodies overlap or are found adjacent to Cajal bodies.
Tissue Specificity Strongly expressed in peripheral blood leukocytes, spleen, thymus, and ovary. Expressed at basal levels in other tissues. {ECO:0000269|PubMed:7797467}.

E3 ubiquitin-protein ligase TRIM22, TRIM22, Human, ELISA Kit - E5012h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t
Range 0.312-20 ng/mL

TRIM22 (Human) IP-WB Antibody Pair - H00010346-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

tripartite motif-containing 22, ELISA Kit - MBS9336494 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human STAF50 / TRIM22 ELISA Kit (Sandwich ELISA) - LS-F13481 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.312-20 ng/ml

TRIM22 - EKH4608 from Nordic BioSite

Sensitivity 0.188ng/ml
Range 0.312-20ng/ml

TRIM22 ELISA Kit (Human) : 96 Wells (OKEH00575) - OKEH00575 from Aviva Systems Biology

Category ELISA Kit
Prices $450.00
Sizes 96 wells
Sensitivity < 0.11 ng/mL
Range 0.31 - 20 ng/mL

Human TRIM22 ELISA Kit - E012652 from Biobool

Category ELISA Kit

Human E3 ubiquitin-protein ligase TRIM22 ELISA Kit - EK4651 from Signalway Antibody

Category ELISA Kit
Prices $659.00
Sizes 1x96t
Range 0.156-10 ng/mL

E3 ubiquitin-protein ligase TRIM22, ELISA Kit - MBS2887702 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.312-20 ng/mL

E3 ubiquitin-protein ligase TRIM22, ELISA Kit - MBS763444 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/ml
Range 0.312-20ng/ml

E3 ubiquitin-protein ligase TRIM22, ELISA Kit - MBS9428477 from MyBioSource

Category ELISA Kit
Prices $605.00
Sizes 96 tests
Sensitivity Less than 0.11ng/mL
Range 0.312-20 ng/mL

Human STAF50 / TRIM22 ELISA Kit (Sandwich ELISA) - LS-F33110 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.188
Range 0.312-20 ng/ml
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