AREL1

Gene Symbol AREL1
Entrez Gene 9870
Alt Symbol KIAA0317
Species Human
Gene Type protein-coding
Description apoptosis resistant E3 ubiquitin protein ligase 1
Other Description apoptosis-resistant E3 ubiquitin protein ligase 1
Swissprots Q7LDY1 O15033 B4E2C7 Q8IYY9
Accessions AAF61276 EAW81186 O15033 AB002315 BAA20775 AK296912 BAG59467 AK304217 BAG65089 BC032944 AAH32944 BI459956 BX248747 CAD66554 XM_005268244 XP_005268301 XM_006720344 XP_006720407 XM_011537415 XP_011535717 XM_011537416 XP_011535718 XM_011537417 XP_011535719 XM_011537418 XP_011535720 NM_014821 NM_001039479 NP_001034568
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation. {ECO:0000269|PubMed:23479728}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:23479728}.

Human KIAA0317 full length protein - ab160690 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160690 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human KIAA0317 protein fragment - ab160691 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160691 on a 12.5% SDS-PAGE stained with Coomassie Blue.

AREL1 / KIAA0317 Antibody Blocking Peptide - LS-E16480 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

AREL1 / KIAA0317 Antibody Blocking Peptide - LS-E16479 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human KIAA0317 Protein - H00009870-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human KIAA0317 Protein - H00009870-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

KIAA0317 Blocking Peptide - 33R-5469 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

KIAA0317 Blocking Peptide - 33R-9768 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

KIAA0317 - H00009870-P01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

KIAA0317 - H00009870-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

KIAA0317 - H00009870-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

KIAA0317 fusion protein - ag19344 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

KIAA0317 fusion protein - ag19906 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Protein KIAA0317(KIAA0317) ,partial - CSB-YP012180HU CSB-EP012180HU CSB-BP012180HU CSB-MP012180HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

KIAA0317 Recombinant Protein Antigen - NBP2-14152PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

KIAA0317 Peptide, Human - M34GP08085H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Protein KIAA0317 (KIAA0317), partial, Recombinant Protein - MBS1003886 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more