Gene Symbol | AREL1 |
---|---|
Entrez Gene | 9870 |
Alt Symbol | KIAA0317 |
Species | Human |
Gene Type | protein-coding |
Description | apoptosis resistant E3 ubiquitin protein ligase 1 |
Other Description | apoptosis-resistant E3 ubiquitin protein ligase 1 |
Swissprots | Q7LDY1 O15033 B4E2C7 Q8IYY9 |
Accessions | AAF61276 EAW81186 O15033 AB002315 BAA20775 AK296912 BAG59467 AK304217 BAG65089 BC032944 AAH32944 BI459956 BX248747 CAD66554 XM_005268244 XP_005268301 XM_006720344 XP_006720407 XM_011537415 XP_011535717 XM_011537416 XP_011535718 XM_011537417 XP_011535719 XM_011537418 XP_011535720 NM_014821 NM_001039479 NP_001034568 |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation. {ECO:0000269|PubMed:23479728}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:23479728}. |
Human KIAA0317 full length protein - ab160690 from Abcam
|
||||||||||
Human KIAA0317 protein fragment - ab160691 from Abcam
|
||||||||||
AREL1 / KIAA0317 Antibody Blocking Peptide - LS-E16480 from LifeSpan Bioscience
|
||||||||||
AREL1 / KIAA0317 Antibody Blocking Peptide - LS-E16479 from LifeSpan Bioscience
|
||||||||||
Recombinant Human KIAA0317 Protein - H00009870-P01 from Novus Biologicals
|
||||||||||
Recombinant Human KIAA0317 Protein - H00009870-Q01 from Novus Biologicals
|
||||||||||
KIAA0317 Blocking Peptide - 33R-5469 from Fitzgerald
|
||||||||||
KIAA0317 Blocking Peptide - 33R-9768 from Fitzgerald
|
||||||||||
KIAA0317 - H00009870-P01 from Acris Antibodies
|
||||||||||
KIAA0317 - H00009870-Q01-10 from Acris Antibodies
|
||||||||||
KIAA0317 - H00009870-Q01-25 from Acris Antibodies
|
||||||||||
KIAA0317 fusion protein - ag19344 from Proteintech Group
|
||||||||||
KIAA0317 fusion protein - ag19906 from Proteintech Group
|
||||||||||
Recombinant Human Protein KIAA0317(KIAA0317) ,partial - CSB-YP012180HU CSB-EP012180HU CSB-BP012180HU CSB-MP012180HU from Cusabio
|
||||||||||
KIAA0317 Recombinant Protein Antigen - NBP2-14152PEP from Novus Biologicals
|
||||||||||
KIAA0317 Peptide, Human - M34GP08085H from Creative Peptides
|
||||||||||
Protein KIAA0317 (KIAA0317), partial, Recombinant Protein - MBS1003886 from MyBioSource
|