AREL1

Gene Symbol AREL1
Entrez Gene 9870
Alt Symbol KIAA0317
Species Human
Gene Type protein-coding
Description apoptosis resistant E3 ubiquitin protein ligase 1
Other Description apoptosis-resistant E3 ubiquitin protein ligase 1
Swissprots Q7LDY1 O15033 B4E2C7 Q8IYY9
Accessions AAF61276 EAW81186 O15033 AB002315 BAA20775 AK296912 BAG59467 AK304217 BAG65089 BC032944 AAH32944 BI459956 BX248747 CAD66554 XM_005268244 XP_005268301 XM_006720344 XP_006720407 XM_011537415 XP_011535717 XM_011537416 XP_011535718 XM_011537417 XP_011535719 XM_011537418 XP_011535720 NM_014821 NM_001039479 NP_001034568
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation. {ECO:0000269|PubMed:23479728}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:23479728}.

KIAA0317 CRISPR/Cas9 KO Plasmid (h) - sc-411371 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 HDR Plasmid (h) - sc-411371-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 Double Nickase Plasmid (h) - sc-411371-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 Double Nickase Plasmid (h2) - sc-411371-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 CRISPR Activation Plasmid (h) - sc-411371-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 CRISPR Activation Plasmid (h2) - sc-411371-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 Lentiviral Activation Particles (h) - sc-411371-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 Lentiviral Activation Particles (h2) - sc-411371-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KIAA0317 siRNA (h) - sc-92294 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIAA0317 shRNA Plasmid (h) - sc-92294-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIAA0317 shRNA (h) Lentiviral Particles - sc-92294-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KIAA0317 RNAi - H00009870-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU075231 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11070 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11070 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AREL1 siRNA (Human) - CRH6619 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AREL1 - MBS8220826 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KIAA0317 (NM_001039479.1) - SHH324531 from Creative biogene

Category siRNA
Species Reactivities Human

Human AREL1 siRNA - orb267121 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AREL1 shRNA Plasmid (Human) - CHH6619 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KIAA0317 miRNA 3'UTR clone - MiUTR1H-05209 from Creative biogene

Species Reactivities Human
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