AREL1

Gene Symbol AREL1
Entrez Gene 9870
Alt Symbol KIAA0317
Species Human
Gene Type protein-coding
Description apoptosis resistant E3 ubiquitin protein ligase 1
Other Description apoptosis-resistant E3 ubiquitin protein ligase 1
Swissprots Q7LDY1 O15033 B4E2C7 Q8IYY9
Accessions AAF61276 EAW81186 O15033 AB002315 BAA20775 AK296912 BAG59467 AK304217 BAG65089 BC032944 AAH32944 BI459956 BX248747 CAD66554 XM_005268244 XP_005268301 XM_006720344 XP_006720407 XM_011537415 XP_011535717 XM_011537416 XP_011535718 XM_011537417 XP_011535719 XM_011537418 XP_011535720 NM_014821 NM_001039479 NP_001034568
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits apoptosis by ubiquitinating and targeting for degradation a number of proapoptotic proteins including DIABLO/SMAC, HTRA2 and SEPT4/ARTS which are released from the mitochondrion into the cytosol following apoptotic stimulation. {ECO:0000269|PubMed:23479728}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:23479728}.

KIAA0317 (N-20) - sc-247252 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

KIAA0317 (P-20) - sc-247253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KIAA0317 antibody - ab119899 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KIAA0317 antibody (ab119899) at 1/1000 dilution + Human fetal heart lysate

Anti-KIAA0317 antibody - ab194430 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-KIAA0317 antibody (ab194430) at 1/500 dilution + U-2 OS cell lysate at 50 µg

Anti-KIAA0317 antibody - ab83801 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KIAA0317 antibody (ab83801) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal heart lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-KIAA0317 antibody - N-terminal - ab155906 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KIAA0317 antibody - N-terminal (ab155906) at 1/1000 dilution + U87-MG whole cell lysate at 30 µg

Anti-AREL1 / KIAA0317 Antibody (aa179-228) - LS-C110993 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
KIAA0317 antibody LS-C110993 Western blot of HT1080 cell lysate.

Anti-AREL1 / KIAA0317 Antibody (aa576-625) - LS-C102148 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIAA0317 antibody LS-C102148 Western blot of Fetal Heart lysate.

Anti-AREL1 / KIAA0317 Antibody (aa551-729) - LS-C178830 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

KIAA0317 Antibody - NBP1-59393 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: KIAA0317 Antibody [NBP1-59393] - Titration: 0.2-1 ug/ml, Positive Control: Human heart.

KIAA0317 Antibody - H00009870-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: KIAA0317 Antibody [H00009870-A01] - KIAA0317 polyclonal antibody (A01), Lot # 051207JC01 Western Blot analysis of KIAA0317 expression in U-2 OS ( Cat # L022V1 ).

KIAA0317 Antibody - NBP2-14152 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: KIAA0317 Antibody [NBP2-14152] Staining of human kidney shows strong membranous positivity in glomeruli.

KIAA0317 Antibody - NBP2-17045 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: KIAA0317 Antibody [NBP2-17045] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.

Anti-KIAA0317, (N-terminal) antibody produced in rabbit - SAB2105611 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA0317 (N-Terminal): <B>Cat. No. SAB2105611</B>: KIAA0317 in HT1080 cell lysates with KIAA0317 antibody at 1.0 μg/mL.

Anti-KIAA0317 (N-terminal) antibody produced in rabbit - SAB2701388 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA0317 (N-terminal): <B>Cat. No. SAB2701388</B>: Western Blot analysis of KIAA0317 in extracts from <B>Lanes</B><BR/>A. U87-MG using <B>Cat. No. SAB2701388</B> at a 1:1000 dilution.

Anti-KIAA0317 antibody produced in rabbit - SAB2101246 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA0317: <B>Cat. No.SAB2101246</B>: KIAA0317 in Fetal Heart tissue lysate with KIAA0317 antibody at 1.0 μg/mL.

Anti-KIAA0317 antibody produced in rabbit - HPA051306 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KIAA0317:<B>Cat. No. HPA051306</B>: Immunohistochemical staining of human kidney shows strong membranous positivity in glomeruli.

KIAA0317 antibody - N-terminal region (ARP44874_P050) - ARP44874_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KIAA0317 antibody - middle region (ARP44875_P050) - ARP44875_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KIAA0317 antibody [N1N2], N-term - GTX119103 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-KIAA0317 antibody [N1N2], N-term used in Western blot. GTX119103

KIAA0317 antibody, Internal - GTX46607 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

KIAA0317 antibody, N-term - GTX46608 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

KIAA0317 antibody - orb78173 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded fetal brain showing membrane staining using KIAA0317 antibody

KIAA0317 antibody - 70R-6288 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

KIAA0317 antibody - 70R-6284 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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