Gene Symbol | ADAM2 |
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Entrez Gene | 2515 |
Alt Symbol | CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase domain 2 |
Other Description | cancer/testis antigen 15|disintegrin and metalloproteinase domain-containing protein 2|fertilin subunit beta |
Swissprots | Q9UQQ8 P78326 Q99965 |
Accessions | CBH30599 EAW63273 EAW63274 EAW63275 Q99965 AJ133005 CAB40813 AK301734 BAG63199 BC034957 AAH34957 BC064547 AAH64547 BG719616 BI460477 DQ891615 ABM82541 DQ894807 ABM85733 U38805 AAD04206 U52370 AAC51110 X99374 CAA67753 XM_005273468 XP_005273525 XM_006725119 XP_006725182 XM_011544479 XP_011542781 XM_011544480 XP_011542782 XM_011546571 XP_011544873 XM_011546572 XP_011544874 NM_001278113 NP_001265042 NM_001278114 NP_001265043 NM_001464 NP_001455 |
Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues. |
ADAM2 (C-15) - sc-25131 from Santa Cruz Biotechnology
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Anti-ADAM2 antibody - ab50642 from Abcam
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Anti-ADAM2 antibody - ab50646 from Abcam
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Anti-ADAM2 antibody - ab169969 from Abcam
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Anti-ADAM2 antibody - ab171901 from Abcam
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Anti-ADAM2 antibody - ab50640 from Abcam
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Anti-ADAM2 antibody - ab50644 from Abcam
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Anti-ADAM2 antibody - ab55028 from Abcam
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Anti-ADAM2 / Fertilin Beta Antibody - LS-C3520 from LifeSpan Bioscience
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Anti-ADAM2 / Fertilin Beta Antibody (N-Terminus) - LS-C151128 from LifeSpan Bioscience
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Anti-ADAM2 / Fertilin Beta Antibody (aa262-311) - LS-C81753 from LifeSpan Bioscience
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Anti-ADAM2 / Fertilin Beta Antibody (aa701-715) - LS-C313499 from LifeSpan Bioscience
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Anti-ADAM2 / Fertilin Beta Antibody (clone 1B8) - LS-C139481 from LifeSpan Bioscience
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ADAM2 Antibody - NBP1-85416 from Novus Biologicals
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ADAM2 Antibody - NBP1-85415 from Novus Biologicals
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ADAM2 Antibody - NBP1-59224 from Novus Biologicals
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ADAM2 Antibody (4A2) - H00002515-M01 from Novus Biologicals
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ADAM2 Antibody - H00002515-B01 from Novus Biologicals
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ADAM2 Antibody - H00002515-B01P from Novus Biologicals
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ADAM2 Antibody - H00002515-A01 from Novus Biologicals
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ADAM2 Polyclonal Antibody - bs-5851R from Bioss
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Monoclonal Anti-ADAM2 antibody produced in mouse - SAB1403842 from Sigma-Aldrich
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Monoclonal Anti-ADAM2 antibody produced in mouse - WH0002515M1 from Sigma-Aldrich
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Anti-ADAM2 antibody produced in rabbit - HPA026581 from Sigma-Aldrich
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Anti-ADAM2 antibody produced in rabbit - HPA024621 from Sigma-Aldrich
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