Gene Symbol | ADAM2 |
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Entrez Gene | 2515 |
Alt Symbol | CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase domain 2 |
Other Description | cancer/testis antigen 15|disintegrin and metalloproteinase domain-containing protein 2|fertilin subunit beta |
Swissprots | Q9UQQ8 P78326 Q99965 |
Accessions | CBH30599 EAW63273 EAW63274 EAW63275 Q99965 AJ133005 CAB40813 AK301734 BAG63199 BC034957 AAH34957 BC064547 AAH64547 BG719616 BI460477 DQ891615 ABM82541 DQ894807 ABM85733 U38805 AAD04206 U52370 AAC51110 X99374 CAA67753 XM_005273468 XP_005273525 XM_006725119 XP_006725182 XM_011544479 XP_011542781 XM_011544480 XP_011542782 XM_011546571 XP_011544873 XM_011546572 XP_011544874 NM_001278113 NP_001265042 NM_001278114 NP_001265043 NM_001464 NP_001455 |
Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues. |
Disintegrin and metalloproteinase domain-containing protein 2 (ADAM2), Human, ELISA Kit - CSB-EL001280HU from ARP American Research Products
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ADAM metallopeptidase domain 2, ELISA Kit - MBS909929 from MyBioSource
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Breast Cancer Antigen CA15-3 Enzyme Immunoassay Test Kit - GWB-150A4D from Genway Biotech
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Disintegrin and metalloproteinase domain-containing protein 2, ELISA Kit - MBS282850 from MyBioSource
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Human Disintegrin and metalloproteinase domain-containing protein 2(ADAM2) ELISA kit - CSB-EL001280HU from Cusabio
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Human ADAM2 ELISA Kit - E000016 from Biobool
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Disintegrin and metalloproteinase domain-containing protein 2, ELISA Kit - MBS284005 from MyBioSource
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