Rnls

Gene Symbol Rnls
Entrez Gene 67795
Alt Symbol 6530404N21Rik, AI452315, AW060440, C10orf59
Species Mouse
Gene Type protein-coding
Description renalase, FAD-dependent amine oxidase
Other Description MAO-C|alpha-NAD(P)H oxidase/anomerase|mMAO-C|monoamine oxidase-C|renalase|rnls
Swissprots A7RDN6 Q80W75 Q3TD88
Accessions A7RDN6 AK014866 AK018322 AK170321 BAE41716 BC052355 AAH52355 DQ788834 ABG82016 NM_001146342 NP_001139814 NM_001167818 NP_001161290
Function Catalyzes the oxidation of the less abundant alpha- NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis (By similarity). {ECO:0000250}.
Subcellular Location Secreted {ECO:0000269|PubMed:17846919}.
Tissue Specificity Expressed predominantly in kidney and testis with lower levels in liver, heart and embryo and weak expression in brain and skeletal muscle. {ECO:0000269|PubMed:17846919}.

Renalase CRISPR/Cas9 KO Plasmid (m) - sc-426746 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase HDR Plasmid (m) - sc-426746-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase Double Nickase Plasmid (m) - sc-426746-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase Double Nickase Plasmid (m2) - sc-426746-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase CRISPR Activation Plasmid (m) - sc-426746-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase CRISPR Activation Plasmid (m2) - sc-426746-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase Lentiviral Activation Particles (m) - sc-426746-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase Lentiviral Activation Particles (m2) - sc-426746-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Renalase siRNA (m) - sc-76385 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Renalase shRNA Plasmid (m) - sc-76385-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Renalase shRNA (m) Lentiviral Particles - sc-76385-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN40379 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40379 from Sigma-Aldrich

Category ZFN Kit
Prices $4,120.00
Sizes 1 kt

RNLS siRNA (Mouse) - CRM7350 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

RNLS - MBS828009 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse RNLS (NM_001146342.2) - SHH397492 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse RNLS siRNA - orb286826 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

RNLS shRNA Plasmid (Mouse) - CHM7350 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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