Gene Symbol | DYNLRB1 |
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Entrez Gene | 83658 |
Alt Symbol | BITH, BLP, DNCL2A, DNLC2A, ROBLD1 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, light chain, roadblock-type 1 |
Other Description | ROBL/LC7-like 1|bithoraxoid-like protein|dynein light chain roadblock-type 1|dynein, cytoplasmic, light polypeptide 2A|dynein-associated protein Km23|roadblock domain-containing protein 1 |
Swissprots | Q5TC72 B1AKR5 Q96IV3 Q9NQM2 Q9NP97 |
Accessions | EAW76267 Q9NP97 AF132750 AAL75951 AF161511 AAF29126 AF165516 AAF86646 AF178431 AAK95342 AK026864 AK097281 AK294214 BAG57523 AY026513 AAK18712 BC002481 AAH02481 BC007223 BG110161 BG419592 BM561321 BM791453 BQ639804 BU163605 CB149456 XM_005260568 XP_005260625 NM_001281727 NP_001268656 NM_001281728 NP_001268657 NM_001281729 NP_001268658 NM_014183 NP_054902 NM_177953 NP_808852 NR_104032 |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. {ECO:0000269|PubMed:11750132}. |
DNLC2A (L-12) - sc-85546 from Santa Cruz Biotechnology
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Anti-DYNLRB1 antibody - ab133903 from Abcam
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Anti-DYNLRB1 Antibody (aa23-72) - LS-C152007 from LifeSpan Bioscience
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Anti-DYNLRB1 Antibody (N-Terminus) - LS-C152006 from LifeSpan Bioscience
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Anti-DYNLRB1 (9-20) antibody produced in rabbit - SAB1102751 from Sigma-Aldrich
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Anti-DYNLRB1 (31-45) antibody produced in rabbit - SAB1102752 from Sigma-Aldrich
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DYNLRB1 Antibody - N-terminal region (ARP65557_P050) - ARP65557_P050 from Aviva Systems Biology
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DYNLRB1 Antibody - N-terminal region (ARP65558_P050) - ARP65558_P050 from Aviva Systems Biology
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DYNLRB1 antibody - 15049-1-AP from Acris Antibodies
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Purified anti-Cytoplasmic Dynein Intermediate Chain Antibody - 904901 from Biolegend
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DYNLRB1 antibody - 15049-1-AP from Proteintech Group
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DYNLRB1, Polyclonal Antibody - MBS2521717 from MyBioSource
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DYNLRB1 Antibody - EPP12511 from Elabscience
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Anti-DYNLRB1 (aa 23-72) polyclonal antibody - DPABH-25472 from Creative Diagnostics
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DYNLRB1 Antibody,Biotin conjugated - CSB-PA865093HD01HU from Cusabio
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DYNLRB1 Antibody,FITC conjugated - CSB-PA865093HC01HU from Cusabio
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DYNLRB1 Antibody,HRP conjugated - CSB-PA865093HB01HU from Cusabio
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DYNLRB1 Antibody - CSB-PA865093HA01HU from Cusabio
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DYNLRB1 - A9069 from NeoScientific
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DYNLRB1 Polyclonal Antibody - A9069 from ABclonal
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DYNLRB1 Antibody - abx124814 from Abbexa
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DYNLRB1 antibody - TA338095 from Acris Antibodies
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DYNLRB1 antibody - TA338096 from Acris Antibodies
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DYNLRB1 Antibody - 45947 from Signalway Antibody
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DYNLRB1 Antibody - DF9471 from Affinity Biosciences
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