Gene Symbol | DYNLRB1 |
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Entrez Gene | 83658 |
Alt Symbol | BITH, BLP, DNCL2A, DNLC2A, ROBLD1 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, light chain, roadblock-type 1 |
Other Description | ROBL/LC7-like 1|bithoraxoid-like protein|dynein light chain roadblock-type 1|dynein, cytoplasmic, light polypeptide 2A|dynein-associated protein Km23|roadblock domain-containing protein 1 |
Swissprots | Q5TC72 B1AKR5 Q96IV3 Q9NQM2 Q9NP97 |
Accessions | EAW76267 Q9NP97 AF132750 AAL75951 AF161511 AAF29126 AF165516 AAF86646 AF178431 AAK95342 AK026864 AK097281 AK294214 BAG57523 AY026513 AAK18712 BC002481 AAH02481 BC007223 BG110161 BG419592 BM561321 BM791453 BQ639804 BU163605 CB149456 XM_005260568 XP_005260625 NM_001281727 NP_001268656 NM_001281728 NP_001268657 NM_001281729 NP_001268658 NM_014183 NP_054902 NM_177953 NP_808852 NR_104032 |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. {ECO:0000269|PubMed:11750132}. |
Human DYNLRB1 full length protein - ab98120 from Abcam
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DYNLRB1 Antibody Blocking Peptide - LS-E23856 from LifeSpan Bioscience
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DYNLRB1 Antibody Blocking Peptide - LS-E23857 from LifeSpan Bioscience
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Dynein light chain 2a cytoplasmic Recombinant Protein - H00083658-P01 from Novus Biologicals
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Recombinant Human Dynein light chain 2a cytoplasmic Protein - NBP1-45306 from Novus Biologicals
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DYNLRB1 Protein (OPPA00139) - OPPA00139 from Aviva Systems Biology
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Human DYNLRB1 protein - orb246630 from Biorbyt
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Human Dynein Light Chain Roadblock-Type 1 protein - orb81074 from Biorbyt
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DYNLRB1 protein (His tag) - 80R-1416 from Fitzgerald
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DYNLRB1 (1-96, His-tag) - AR09592PU-L from Acris Antibodies
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DYNLRB1 (1-96, His-tag) - AR09592PU-N from Acris Antibodies
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DYNLRB1 - H00083658-P01-10 from Acris Antibodies
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DYNLRB1 - H00083658-P01-25 from Acris Antibodies
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DYNLRB1, 1-96aa, Human, His tag, E.coli - 01-2150 from ARP American Research Products
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DYNLRB1 fusion protein - Ag7032 from Proteintech Group
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DYNLRB1 fusion protein - Ag7090 from Proteintech Group
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DYNLRB1 Human - PRPS-496 from NeoScientific
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Recombinant Human Dynein Light Chain Roadblock-Type 1 Protein - BP001945-PRO-489 from Syd Labs
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DYNLRB1, 1-96aa, Recombinant Protein - GWB-P1384F from Genway Biotech
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DYNLRB1 Human Protein - GWB-BSP458 from Genway Biotech
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Dynein Light Chain Dnlc2a - CBCRY31 from Creative Biomart
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Recombinant Human DYNLRB1, GST-tagged - DYNLRB1-12233H from Creative Biomart
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Recombinant Human DYNLRB1, His-tagged - DYNLRB1-2750H from Creative Biomart
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DYNLRB1 - NKX-946 from Reagent Proteins
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DYNLRB1 1-96aa - CMB-487 from Reagent Proteins
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