METRNL

Gene Symbol	METRNL
Entrez Gene	284207
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	meteorin, glial cell differentiation regulator-like
Other Description	meteorin-like protein|subfatin
Swissprots	Q86VM0 B3KSJ5 Q641Q3
Accessions	CAB58552 CBJ57243 CDM22127 EAW89833 Q641Q3 AF086149 AK093748 BAG52757 BC050568 AAH50568 BC082252 AAH82252 BC118558 AAI18559 BC118638 AAI18639 CF264755 DR760693 XM_005256349 XP_005256406 XM_006725291 XP_006725354 XM_011523562 XP_011521864 XM_011546763 XP_011545065 NM_001004431 NP_001004431
Function	Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti- inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures (By similarity). {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000250}.
Tissue Specificity	Highly expressed in the skeletal muscle, in subcutaneous adipose tissue, epididymal white adipose tissue depots and heart. Also expressed in brown adipose tissues and kidney. {ECO:0000269|PubMed:24393292, ECO:0000269|PubMed:24906147}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mammal METRNL protein - orb246922 from Biorbyt Category Protein Prices $502.00, $774.00, $1,054.00 Sizes 20 μg, 50 μg, 100 μg Species Human

Human METRNL protein - orb244856 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Recombinant Human Meteorin-like protein(METRNL) - CSB-YP731035HU CSB-BP731035HU CSB-EP731035HU from Cusabio Category Protein Source Yeast or Baculovirus or E.coli Species Human

Recombinant human Meteorin-like protein - CSB-EP731035HU from Cusabio Category Protein Source E.coli Species Human

Meteorin-like/METRNL Protein - NBP1-91064PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

METRNL Peptide, Human - M34GP09420H from Creative Peptides Category Peptide Source Synthetic. Species Human

METRNL Recombinant Protein (OPCA02303) - OPCA02303 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

METRNL Recombinant Protein (OPCA03027) - OPCA03027 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

METRNL Recombinant Protein (OPCA03648) - OPCA03648 from Aviva Systems Biology Category Protein Prices $445.00 Sizes 20 µg Source Human

Recombinant Human Meteorin-like/METRNL Protein, CF - 9339-MN from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Human Meteorin-like/METRNL (Gln46-Asp311) Accession # Q641Q3 HP GGGSGGGSGGGS HHHHHH N-terminus C-terminus Species Human

Recombinant human Meteorin-like protein - AP71340 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Homo sapiens Meteorin-like protein - AP73076 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

Recombinant Meteorin-like protein - AP73195 from Signalway Antibody Category Protein Prices $470.00, $935.00, $1,305.00 Sizes 20 µg, 50 µg, 100 µg Source Mammalian cell

Meteorin, Recombinant Protein - MBS9422871 from MyBioSource Category Protein Prices $450.00, $830.00, $1,135.00 Sizes 20 µg, 50 µg, 100 µg Source Mammalian Cell Species Human

Meteorin, Recombinant Protein - MBS9421207 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Meteorin, Recombinant Protein - MBS9422772 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Meteorin-like protein, Recombinant Protein - MBS1387703 from MyBioSource Category Protein Prices $110.00, $140.00, $190.00, $285.00, $295.00, $460.00, $575.00, $750.00, $795.00, $950.00, $1,180.00, $1,860.00, $2,760.00 Sizes 10 µg (E-Coli), 100 µg (Baculovirus), 50 µg (E-Coli), 100 µg (E-Coli), 20 µg (Mammalian-Cell), 200 µg (Yeast), 50 µg (Mammalian-Cell), 500 µg (Yeast), 100 µg (Mammalian-Cell), 50 µg (Baculovirus), 1 mg (E-Coli), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Mouse Meteorin-like/METRNL Protein, CF - 6679-MN from Novus Biologicals Category Protein Prices $329.00 Sizes 25 µg

Recombinant Human Meteorin-like/METRNL Protein, CF - 9339-MN from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg Species Human

Human METRNL protein - orb358297 from Biorbyt Category Protein Species Human

Recombinant Human METRNL Protein (46-311 aa), His-tagged - METRNL-1675H from Creative Biomart Category Protein Source Yeast Species Human

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