EDEM3

Gene Symbol	EDEM3
Entrez Gene	80267
Alt Symbol	C1orf22
Species	Human
Gene Type	protein-coding
Description	ER degradation enhancer, mannosidase alpha-like 3
Other Description	ER degradation-enhancing -mannosidase-like protein 3|ER degradation-enhancing alpha-mannosidase-like 3|ER degradation-enhancing alpha-mannosidase-like protein 3|alpha-1,2-mannosidase EDEM3
Swissprots	Q9HCW1 Q7L2Y5 B7ZLZ2 Q0VGM5 Q9UFV7 B2RCH6 Q5TEZ0 Q9BZQ6
Accessions	EAW91178 EAW91179 EAW91180 EAW91181 EAW91182 EAW91183 Q9BZQ6 AF288393 AAG60613 AI521228 AK000945 BAA91438 AK023095 BAB14402 AK225171 AK315118 BAG37573 AL117441 CAB55926 BC016464 AAH16464 BC070173 BC105586 AAI05587 BC144149 AAI44150 BC144150 BC160020 AAI60020 DA724785 DB292148 XM_005245499 XP_005245556 XM_011510010 XP_011508312 XM_011510011 XP_011508313 XM_011510012 XP_011508314 XM_011510013 XP_011508315 XM_011510014 XP_011508316 XM_011510015 XP_011508317 NM_025191 NP_079467
Function	Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity (By similarity). {ECO:0000250, ECO:0000269|PubMed:25092655}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EDEM3 full length protein - ab164239 from Abcam Category Protein Source Wheat germ Species Human

EDEM3 Antibody Blocking Peptide - LS-E4279 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EDEM3 Antibody Blocking Peptide - LS-E22827 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EDEM3 Recombinant Protein - H00080267-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EDEM3-Antibody-C-term-Blocking-Peptide - BP16556b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EDEM3 - H00080267-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

EDEM3 - H00080267-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

EDEM3 fusion protein - ag2815 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

EDEM3 fusion protein - ag9131 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human ER degradation-enhancing alpha-mannosidase-like 3(EDEM3) ,partial - CSB-YP863170HU CSB-EP863170HU CSB-BP863170HU CSB-MP863170HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

EDEM3 Blocking Peptide - 3614BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 μg

EDEM3, Peptide - MBS843859 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

EDEM3 Protein - NBP1-88342PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

EDEM3 Recombinant Protein Antigen - NBP1-88341PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

EDEM3 Peptide, Human - M34GP04714H from Creative Peptides Category Peptide Source Synthetic. Species Human

EDEM3 fusion protein - Ag26123 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

EDEM3 Recombinant Protein Antigen - NBP2-58282PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ER degradation-enhancing alpha-mannosidase-like 3 (EDEM3), partial, Recombinant Protein - MBS1279842 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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