EDEM3

Gene Symbol EDEM3
Entrez Gene 80267
Alt Symbol C1orf22
Species Human
Gene Type protein-coding
Description ER degradation enhancer, mannosidase alpha-like 3
Other Description ER degradation-enhancing -mannosidase-like protein 3|ER degradation-enhancing alpha-mannosidase-like 3|ER degradation-enhancing alpha-mannosidase-like protein 3|alpha-1,2-mannosidase EDEM3
Swissprots Q9HCW1 Q7L2Y5 B7ZLZ2 Q0VGM5 Q9UFV7 B2RCH6 Q5TEZ0 Q9BZQ6
Accessions EAW91178 EAW91179 EAW91180 EAW91181 EAW91182 EAW91183 Q9BZQ6 AF288393 AAG60613 AI521228 AK000945 BAA91438 AK023095 BAB14402 AK225171 AK315118 BAG37573 AL117441 CAB55926 BC016464 AAH16464 BC070173 BC105586 AAI05587 BC144149 AAI44150 BC144150 BC160020 AAI60020 DA724785 DB292148 XM_005245499 XP_005245556 XM_011510010 XP_011508312 XM_011510011 XP_011508313 XM_011510012 XP_011508314 XM_011510013 XP_011508315 XM_011510014 XP_011508316 XM_011510015 XP_011508317 NM_025191 NP_079467
Function Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity (By similarity). {ECO:0000250, ECO:0000269|PubMed:25092655}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Top Pathways Protein processing in endoplasmic reticulum

EDEM3 CRISPR/Cas9 KO Plasmid (h) - sc-408476 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 HDR Plasmid (h) - sc-408476-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 Double Nickase Plasmid (h) - sc-408476-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 Double Nickase Plasmid (h2) - sc-408476-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 CRISPR Activation Plasmid (h) - sc-408476-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 CRISPR Activation Plasmid (h2) - sc-408476-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 Lentiviral Activation Particles (h) - sc-408476-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 Lentiviral Activation Particles (h2) - sc-408476-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EDEM3 siRNA (h) - sc-78683 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDEM3 shRNA Plasmid (h) - sc-78683-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDEM3 shRNA (h) Lentiviral Particles - sc-78683-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EDEM3 RNAi - H00080267-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU089151 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU099891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU124321 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7653 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7653 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EDEM3 siRNA (Human) - CRJ2831 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EDEM3 - MBS8216369 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EDEM3(NM_025191.3) - SHH023573 from Creative biogene

Category siRNA
Species Reactivities Human

EDEM3 shRNA Plasmid (Human) - CHJ2831 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EDEM3 miRNA 3'UTR clone - MiUTR1H-03103 from Creative biogene

Species Reactivities Human
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