PPP1R13L

Gene Symbol PPP1R13L
Entrez Gene 10848
Alt Symbol IASPP, NKIP1, RAI, RAI4
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 13 like
Other Description NFkB interacting protein 1|NFkB-interacting protein 1|PPP1R13B-like protein|inhibitor of ASPP protein|inhibitor of apoptosis stimulating protein of p53|protein iASPP|protein phosphatase 1, regulatory (inhibitor) subunit 13 like|relA-associated inhibitor|retinoic acid induced 4
Swissprots Q9Y290 Q2PNZ9 Q8WUF5 Q6PKF8 Q5DU71 Q6P1R7 Q5I1X4
Accessions ABC40745 EAW57343 EAW57344 EAW57345 Q8WUF5 AF078036 AAD27004 AF078037 AAD27005 AJ888472 CAI60219 AK130326 BAC85327 AY869712 AAW51146 BC001475 AAH01475 BC014499 BC020259 BC020589 AAH20589 BC032298 AAH32298 BC064913 AAH64913 DB209153 DQ986418 ABK76301 NM_001142502 NP_001135974 NM_006663 NP_006654
Function Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. {ECO:0000269|PubMed:10336463, ECO:0000269|PubMed:12134007, ECO:0000269|PubMed:12524540, ECO:0000269|PubMed:15489900}.
Subcellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic but also nuclear.
Tissue Specificity Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. {ECO:0000269|PubMed:10336463}.

Human iASPP full length protein - ab153136 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153136 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human iASPP protein fragment - ab153137 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153137 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human iASPP Protein - H00010848-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human iASPP Protein - H00010848-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

PPP1R13L - H00010848-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

PPP1R13L - H00010848-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PPP1R13L - H00010848-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PPP1R13L fusion protein - Ag13273 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PPP1R13L fusion protein - ag0635 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human PPP1R13L, His-tagged - PPP1R13L-1903H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human RelA-associated inhibitor(PPP1R13L) ,partial - CSB-YP851965HU CSB-EP851965HU CSB-BP851965HU CSB-MP851965HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

iASPP Protein - NBP2-38879PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

iASPP Recombinant Protein Antigen - NBP2-48732PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E. coli
Species Human

PPP1R13L-Blocking-Peptide-Center - BP21505c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PPP1R13L-Blocking-Peptide-N-Term - BP21503a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PPP1R13L Peptide, Human - M34GP12235H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

RelA-associated inhibitor (PPP1R13L), partial, Recombinant Protein - MBS1453777 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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