PPP1R13L

Gene Symbol PPP1R13L
Entrez Gene 10848
Alt Symbol IASPP, NKIP1, RAI, RAI4
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 13 like
Other Description NFkB interacting protein 1|NFkB-interacting protein 1|PPP1R13B-like protein|inhibitor of ASPP protein|inhibitor of apoptosis stimulating protein of p53|protein iASPP|protein phosphatase 1, regulatory (inhibitor) subunit 13 like|relA-associated inhibitor|retinoic acid induced 4
Swissprots Q9Y290 Q2PNZ9 Q8WUF5 Q6PKF8 Q5DU71 Q6P1R7 Q5I1X4
Accessions ABC40745 EAW57343 EAW57344 EAW57345 Q8WUF5 AF078036 AAD27004 AF078037 AAD27005 AJ888472 CAI60219 AK130326 BAC85327 AY869712 AAW51146 BC001475 AAH01475 BC014499 BC020259 BC020589 AAH20589 BC032298 AAH32298 BC064913 AAH64913 DB209153 DQ986418 ABK76301 NM_001142502 NP_001135974 NM_006663 NP_006654
Function Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. {ECO:0000269|PubMed:10336463, ECO:0000269|PubMed:12134007, ECO:0000269|PubMed:12524540, ECO:0000269|PubMed:15489900}.
Subcellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic but also nuclear.
Tissue Specificity Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. {ECO:0000269|PubMed:10336463}.

iASPP CRISPR/Cas9 KO Plasmid (h) - sc-404703 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP HDR Plasmid (h) - sc-404703-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP Double Nickase Plasmid (h) - sc-404703-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP Double Nickase Plasmid (h2) - sc-404703-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP CRISPR Activation Plasmid (h) - sc-404703-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP CRISPR Activation Plasmid (h2) - sc-404703-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP Lentiviral Activation Particles (h) - sc-404703-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP Lentiviral Activation Particles (h2) - sc-404703-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

iASPP siRNA (h) - sc-72100 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

iASPP shRNA Plasmid (h) - sc-72100-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

iASPP shRNA (h) Lentiviral Particles - sc-72100-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

iASPP RNAi - H00010848-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU086721 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® Human Phosphatase - SIHP0539 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0540 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0538 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17263 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17263 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05312 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05312

PPP1R13L siRNA (Human) - CRH7388 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human PPP1R13L siRNA - orb267890 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPP1R13L shRNA Plasmid (Human) - CHH7388 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PPP1R13L miRNA 3'UTR clone - MiUTR1H-08175 from Creative biogene

Species Reactivities Human

PPP1R13L miRNA 3'UTR clone - MiUTR1H-08176 from Creative biogene

Species Reactivities Human
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