Gene Symbol | SKA3 |
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Entrez Gene | 221150 |
Alt Symbol | C13orf3, RAMA1 |
Species | Human |
Gene Type | protein-coding |
Description | spindle and kinetochore associated complex subunit 3 |
Other Description | spindle and kinetochore-associated protein 3 |
Swissprots | Q5VZV5 A2A331 A2A330 Q8IX90 Q8NBG1 B2RBY2 Q86WR2 Q96D22 |
Accessions | EAX08293 EAX08294 EAX08295 Q8IX90 AF361358 AAO13796 AK090584 BAC03484 AK307976 AK314864 BAG37379 BC013418 AAH13418 BC048988 AAH48988 BI460315 HQ447993 ADQ32474 XM_005266288 XP_005266345 XM_011534994 XP_011533296 NM_001166017 NP_001159489 NM_145061 NP_659498 |
Function | Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. {ECO:0000269|PubMed:19289083, ECO:0000269|PubMed:19360002}. |
Subcellular Location | Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. |
RAMA1 / SKA3 Antibody Blocking Peptide - LS-E27158 from LifeSpan Bioscience
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RAMA1 / SKA3 Antibody Blocking Peptide - LS-E30780 from LifeSpan Bioscience
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RAMA1 / SKA3 Antibody Blocking Peptide - LS-E9882 from LifeSpan Bioscience
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RAMA1 / SKA3 Antibody Blocking Peptide - LS-E20045 from LifeSpan Bioscience
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SKA3 Blocking Peptide - NBP1-76311PEP from Novus Biologicals
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C13orf3-Antibody-Center-Blocking-Peptide - BP8979c from Abgent, a WuXi AppTec company
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SKA3 blocking peptide - GTX88366-PEP from GeneTex
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SKA3 Peptide - GTX85013-PEP from GeneTex
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C13orf3 Immunizing peptide - orb59552 from Biorbyt
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SKA3 Blocking Peptide - 33R-2779 from Fitzgerald
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SKA3 Peptide - AC21-1978-P from Abcore
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SKA3 Control Peptide - AP30789CP-N from Acris Antibodies
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SKA3 Peptide - 5405P from ProSci
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SKA3 Peptide - 42-185P from ProSci
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C13orf3 fusion protein - Ag23713 from Proteintech Group
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Recombinant Human Spindle and kinetochore-associated protein 3(SKA3) - CSB-YP816899HU CSB-EP816899HU CSB-BP816899HU CSB-MP816899HU from Cusabio
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SKA3 - TP322931 from Acris Antibodies
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SKA3 (transcript variant 2) - TP328314 from Acris Antibodies
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SKA3, Peptide - MBS426615 from MyBioSource
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SKA3 Protein - NBP1-88399PEP from Novus Biologicals
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SKA3 Recombinant Protein Antigen - NBP1-88398PEP from Novus Biologicals
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SKA3 Peptide, Human - M34GP14284H from Creative Peptides
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Spindle and kinetochore-associated protein 3 (SKA3), Recombinant Protein - MBS1442455 from MyBioSource
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C13orf3 fusion protein - Ag23684 from Proteintech Group
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