Gene Symbol | Rgn |
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Entrez Gene | 19733 |
Alt Symbol | AI265316, GNL, SMP30 |
Species | Mouse |
Gene Type | protein-coding |
Description | regucalcin |
Other Description | RC|SMP-30|gluconolactonase|senescence marker protein 30 |
Swissprots | A2AFC8 Q64374 Q3UJG3 Q60944 |
Accessions | AAD03478 EDL00749 Q64374 AK146465 BAE27192 BC012710 AAH12710 D86217 BAA13046 U28937 AAC52721 XM_006527572 XP_006527635 NM_009060 NP_033086 |
Function | Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Mainly present in the liver. Weak expression was found in the brain, lung and kidney. {ECO:0000269|PubMed:8765750, ECO:0000269|PubMed:9278263}. |
Top Pathways | Pentose phosphate pathway, Ascorbate and aldarate metabolism, Carbon metabolism, Degradation of aromatic compounds |
Recombinant Mouse Regucalcin(Rgn) - CSB-YP737355MO CSB-EP737355MO CSB-BP737355MO CSB-MP737355MO from Cusabio
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Recombinant Mouse RGN Protein - RGN-14128M from Creative Biomart
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Recombinant Regucalcin (RGN) - RPU51819 from Biomatik
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RGN Recombinant Protein (OPCD00751) - OPCD00751 from Aviva Systems Biology
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Regucalcin (Rgn), Recombinant Protein - MBS1436366 from MyBioSource
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