Rgn

Gene Symbol Rgn
Entrez Gene 19733
Alt Symbol AI265316, GNL, SMP30
Species Mouse
Gene Type protein-coding
Description regucalcin
Other Description RC|SMP-30|gluconolactonase|senescence marker protein 30
Swissprots A2AFC8 Q64374 Q3UJG3 Q60944
Accessions AAD03478 EDL00749 Q64374 AK146465 BAE27192 BC012710 AAH12710 D86217 BAA13046 U28937 AAC52721 XM_006527572 XP_006527635 NM_009060 NP_033086
Function Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Tissue Specificity Mainly present in the liver. Weak expression was found in the brain, lung and kidney. {ECO:0000269|PubMed:8765750, ECO:0000269|PubMed:9278263}.
Top Pathways Pentose phosphate pathway, Ascorbate and aldarate metabolism, Carbon metabolism, Degradation of aromatic compounds

SMP30 CRISPR/Cas9 KO Plasmid (m) - sc-422668 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 HDR Plasmid (m) - sc-422668-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 Double Nickase Plasmid (m) - sc-422668-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 Double Nickase Plasmid (m2) - sc-422668-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 CRISPR Activation Plasmid (m) - sc-422668-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 CRISPR Activation Plasmid (m2) - sc-422668-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 Lentiviral Activation Particles (m) - sc-422668-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 Lentiviral Activation Particles (m2) - sc-422668-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

SMP30 siRNA (m) - sc-153635 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

SMP30 shRNA Plasmid (m) - sc-153635-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

SMP30 shRNA (m) Lentiviral Particles - sc-153635-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU006711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN40142 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40142 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RGN siRNA (Mouse) - CRM3476 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

RGN - MBS8230689 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse RGN (NM_009060.2) - SHH394740 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Rgn(NM_009060.2) - SHR178386 from Creative biogene

Category siRNA
Species Reactivities Mouse

RGN shRNA Plasmid (Mouse) - CHM3476 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

RGN miRNA 3'UTR clone - MiUTR1M-10065 from Creative biogene

Species Reactivities Mouse
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