MYO1E

Gene Symbol MYO1E
Entrez Gene 4643
Alt Symbol FSGS6, HuncM-IC, MYO1C
Species Human
Gene Type protein-coding
Description myosin IE
Other Description MYO1E variant protein|myosin-IC|unconventional myosin 1E|unconventional myosin-Ie
Swissprots Q14778 Q12965
Accessions EAW77564 Q12965 AB290177 BAG06731 AK291688 BAF84377 AL707587 BC067835 BC098392 AAH98392 BQ054624 BX489024 CA429161 CB128582 L29139 AAA20902 U14391 AAA62667 NM_004998 NP_004989
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14. {ECO:0000269|PubMed:11940582, ECO:0000269|PubMed:17257598, ECO:0000269|PubMed:20860408}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction {ECO:0000250}. Note=Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles. {ECO:0000250}.
Tissue Specificity Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes. {ECO:0000269|PubMed:21458045, ECO:0000269|PubMed:21756023}.

Myosin-Ie (MYO1E), Human, ELISA Kit - CSB-EL015342HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

myosin IE, ELISA Kit - MBS906224 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 4.69 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human Myosin-Ie(MYO1E) ELISA kit - CSB-EL015342HU from Cusabio

Category ELISA Kit
Sensitivity 4.69 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human MYO1E ELISA Kit - E025451 from Biobool

Category ELISA Kit
Sensitivity 4.69 pg/ml

MYO1E ELISA Kit (Human) (OKCA01373) - OKCA01373 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 4.69 pg/mL
Range 18.75 - 1,200 pg/mL

Human Myosin-Ie (MYO1E) ELISA Kit - AE31957HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t

Myosin-Ic, ELISA Kit - MBS285068 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human MYO1E ELISA Kit - orb404887 from Biorbyt

Category ELISA Kit
Sensitivity 4.69 pg/ml
Range 18.75 pg/ml-1200 pg/ml
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