MYO1E

Gene Symbol	MYO1E
Entrez Gene	4643
Alt Symbol	FSGS6, HuncM-IC, MYO1C
Species	Human
Gene Type	protein-coding
Description	myosin IE
Other Description	MYO1E variant protein|myosin-IC|unconventional myosin 1E|unconventional myosin-Ie
Swissprots	Q14778 Q12965
Accessions	EAW77564 Q12965 AB290177 BAG06731 AK291688 BAF84377 AL707587 BC067835 BC098392 AAH98392 BQ054624 BX489024 CA429161 CB128582 L29139 AAA20902 U14391 AAA62667 NM_004998 NP_004989
Function	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14. {ECO:0000269|PubMed:11940582, ECO:0000269|PubMed:17257598, ECO:0000269|PubMed:20860408}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction {ECO:0000250}. Note=Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles. {ECO:0000250}.
Tissue Specificity	Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes. {ECO:0000269|PubMed:21458045, ECO:0000269|PubMed:21756023}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MYO1E protein fragment - ab158943 from Abcam Category Protein Source Wheat germ Species Human

MYO1E / Myosin IE Antibody Blocking Peptide - LS-E4351 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MYO1E / Myosin IE Antibody Blocking Peptide - LS-E20573 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Myosin 1E Protein - H00004643-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MYO1E-Antibody-N-term-Blocking-Peptide - BP16650a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Myosin Ie Blocking Peptide - 33R-7176 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Myosin IE Protein - abx068161 from Abbexa Category Protein Source E.coli Species Human

Myosin-Ie - H00004643-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Myosin-Ie - H00004643-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Myosin IE (MYO1E), Human - 20-8789 from ARP American Research Products Category Protein Prices $479.00 Sizes 50 µg Source E.coli Species Human

MYO1E fusion protein - ag12176 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MYO1E fusion protein - Ag12244 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Myosin IE (MYO1E) - RPD434Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Myosin IE (MYO1E) - RPD434Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Human Unconventional myosin-Ie(MYO1E) ,partial - CSB-YP621526HU CSB-EP621526HU CSB-BP621526HU CSB-MP621526HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Myosin IE (MYO1E) - RPU142887 from Biomatik Category Protein Prices $225.50, $451.00, $676.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Myosin 1E Recombinant Protein Antigen - NBP1-92158PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MYO1E Peptide, Human - M34GP10027H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Myosin IE (MYO1E) - RPU42887 from Biomatik Category Protein Prices $180.00, $369.00, $564.00, $672.40 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

MYO1E Recombinant Protein (OPCD05543) - OPCD05543 from Aviva Systems Biology Category Protein Source E.coli Species Human

Myosin IE (MYO1E), Recombinant Protein - MBS2009736 from MyBioSource Category Protein Prices $175.00, $370.00, $575.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

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