MYO1E

Gene Symbol MYO1E
Entrez Gene 4643
Alt Symbol FSGS6, HuncM-IC, MYO1C
Species Human
Gene Type protein-coding
Description myosin IE
Other Description MYO1E variant protein|myosin-IC|unconventional myosin 1E|unconventional myosin-Ie
Swissprots Q14778 Q12965
Accessions EAW77564 Q12965 AB290177 BAG06731 AK291688 BAF84377 AL707587 BC067835 BC098392 AAH98392 BQ054624 BX489024 CA429161 CB128582 L29139 AAA20902 U14391 AAA62667 NM_004998 NP_004989
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14. {ECO:0000269|PubMed:11940582, ECO:0000269|PubMed:17257598, ECO:0000269|PubMed:20860408}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction {ECO:0000250}. Note=Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles. {ECO:0000250}.
Tissue Specificity Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes. {ECO:0000269|PubMed:21458045, ECO:0000269|PubMed:21756023}.

Myosin Ie (Q-12) - sc-32709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Myosin Ie (Q-12): sc-32709. Western blot analysis of Myosin Ie expression in HeLa whole cell lysate.

Myosin Ie (R-60) - sc-66984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Myosin Ie (N-13) - sc-32708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Myosin Ie (N-13): sc-32708. Western blot analysis of Myosin Ie expression in HeLa whole cell lysate.

Myosin Ie (H-60) - sc-66983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-MYO1E antibody - ab129789 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MYO1E antibody (ab129789) at 1/100 dilution + T47D cell lysate at 35 µg

Anti-MYO1E antibody - ab98191 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MYO1E antibody (ab98191) at 1 µg/ml + HepG2 cell lysate at 10 µg

Anti-MYO1E / Myosin IE Antibody (aa227-257, AP) - LS-C207293 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa227-257, APC) - LS-C207294 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa227-257, Biotin) - LS-C207295 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa227-257, FITC) - LS-C207296 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa227-257, PE) - LS-C207298 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa772-1033, Biotin) - LS-C298681 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa781-1036, Biotin) - LS-C298682 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa781-1036, FITC) - LS-C305370 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa772-1033, FITC) - LS-C305372 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa227-257) - LS-C323202 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (aa227-257, Azide-free, HRP) - LS-C207297 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MYO1E / Myosin IE Antibody (C-Terminus) - LS-C107702 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MYO1E antibody LS-C107702 Western blot of HepG2 cell lysate.

Anti-MYO1E / Myosin IE Antibody (aa772-1033) - LS-C295504 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MYO1E / Myosin IE.

Anti-MYO1E / Myosin IE Antibody (aa781-1036) - LS-C295506 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant MYO1E / Myosin IE.

Anti-MYO1E / Myosin IE Antibody (clone 7A5) - LS-C197735 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7A5
Western Blot analysis of MYO1E expression in transfected 293T cell line by MYO1E monoclonal antibody (M02), clone 7A5.Lane 1: MYO1E transfected lysate (Predicted MW: 127.1 KDa).Lane 2: Non-transfected lysate.

Anti-MYO1E / Myosin IE Antibody (aa228-257) IHC-plus™ - LS-B11096 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-MYO1E / Myosin IE antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11096 dilution 1:100.

Myosin 1E Antibody - NBP1-53151 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Myosin 1E Antibody [NBP1-53151] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

Myosin 1E Antibody - NBP1-92158 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Myosin 1E Antibody [NBP1-92158] - Analysis in human cell line A-549.

Myosin 1E Antibody (7A5) - H00004643-M02-100ug from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7A5
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