Gene Symbol | HSD3B2 |
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Entrez Gene | 3284 |
Alt Symbol | HSD3B, HSDB, SDR11E2 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
Other Description | 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II|3-beta-HSD II|3-beta-HSD adrenal and gonadal type|3-beta-hydroxy-5-ene steroid dehydrogenase|3-beta-hydroxy-Delta(5)-steroid dehydrogenase|delta 5-delta 4-isomerase type II|progesterone reductase|short chain dehydrogenase/reductase family 11E, member 2 |
Swissprots | Q9UD08 Q6AI10 A2RRA5 Q53GD4 P26439 Q16010 Q99890 Q6LDB9 |
Accessions | AAA36014 AAC60599 AAC60600 AAD14930 AJF45348 EAW56700 EAW56701 EAW56702 P26439 AK222997 BAD96717 AK313413 BAG36207 AV705363 BC038419 AAH38419 BC131488 AAI31489 BP197992 CF596786 DQ891764 ABM82690 DQ894948 ABM85874 M67466 AAA36016 NM_000198 NP_000189 NM_001166120 NP_001159592 |
Function | 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. |
Tissue Specificity | Expressed in adrenal gland, testis and ovary. |
Top Pathways | Steroid hormone biosynthesis, Ovarian steroidogenesis |
Anti-HSD3B2 Antibody - LS-C311238 from LifeSpan Bioscience
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Anti-HSD3B2 Antibody - LS-C340929 from LifeSpan Bioscience
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Anti-HSD3B2 Antibody - LS-C341455 from LifeSpan Bioscience
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Anti-HSD3B2 Antibody (N-Terminus) - LS-C80649 from LifeSpan Bioscience
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Anti-HSD3B2 Antibody - LS-C331709 from LifeSpan Bioscience
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Anti-HSD3B2 Antibody (clone 1E8) - LS-C197460 from LifeSpan Bioscience
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Beta Hydroxysteroid Dehydrogenase Antibody - NBP1-32353 from Novus Biologicals
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Beta Hydroxysteroid Dehydrogenase Antibody - NBP1-59531 from Novus Biologicals
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Beta Hydroxysteroid Dehydrogenase Antibody - H00003284-D01P from Novus Biologicals
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Beta Hydroxysteroid Dehydrogenase Antibody (1E8.) - H00003284-M02 from Novus Biologicals
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Anti-HSD3B2 antibody produced in rabbit - SAB1401187 from Sigma-Aldrich
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Anti-HSD3B2 (306-320) antibody produced in rabbit - SAB1100096 from Sigma-Aldrich
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Anti-HSD3B2 (256-270) antibody produced in rabbit - SAB1100095 from Sigma-Aldrich
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Anti-HSD3B2 antibody produced in rabbit - SAB2101087 from Sigma-Aldrich
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Monoclonal Anti-HSD3B2 antibody produced in mouse - SAB1402232 from Sigma-Aldrich
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HSD3B2 antibody - N-terminal region (ARP44239_P050) - ARP44239_P050 from Aviva Systems Biology
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HSD3B2 Antibody - middle region (ARP76283_P050) - ARP76283_P050 from Aviva Systems Biology
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HSD3B2 antibody - GTX54092 from GeneTex
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HSD3B2 antibody - GTX102744 from GeneTex
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HSD3B2 antibody [N3C3] - GTX102813 from GeneTex
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Anti -HSD3B2 (3b-HSD, HSD-3b, 3 beta-hydroxysteroid Dehydrogenase/Delta 5->4-IsomeraseType 2, 3 beta-hydroxysteroid Dehydrogenase/Delta 5->4-Isomerase Type II, 3-beta-HSD II,3-beta-HSD adrenal and gonadal Type, 3-beta-hydroxy-Delta(5)-steroid Dehydrogenase, 3 - 223386 from USBiological Life Science
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HSD3B2 Polyclonal Antibody - A1823 from ABclonal
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HSD3B2 antibody - 70R-6441 from Fitzgerald
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HSD3B2 antibody - 70R-17828 from Fitzgerald
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HSD3B2 Antibody - abx001506 from Abbexa
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