HSD3B2

Gene Symbol HSD3B2
Entrez Gene 3284
Alt Symbol HSD3B, HSDB, SDR11E2
Species Human
Gene Type protein-coding
Description hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Other Description 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II|3-beta-HSD II|3-beta-HSD adrenal and gonadal type|3-beta-hydroxy-5-ene steroid dehydrogenase|3-beta-hydroxy-Delta(5)-steroid dehydrogenase|delta 5-delta 4-isomerase type II|progesterone reductase|short chain dehydrogenase/reductase family 11E, member 2
Swissprots Q9UD08 Q6AI10 A2RRA5 Q53GD4 P26439 Q16010 Q99890 Q6LDB9
Accessions AAA36014 AAC60599 AAC60600 AAD14930 AJF45348 EAW56700 EAW56701 EAW56702 P26439 AK222997 BAD96717 AK313413 BAG36207 AV705363 BC038419 AAH38419 BC131488 AAI31489 BP197992 CF596786 DQ891764 ABM82690 DQ894948 ABM85874 M67466 AAA36016 NM_000198 NP_000189 NM_001166120 NP_001159592
Function 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Subcellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Tissue Specificity Expressed in adrenal gland, testis and ovary.
Top Pathways Steroid hormone biosynthesis, Ovarian steroidogenesis

3β-HSD2 siRNA (h) - sc-105008 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

3β-HSD2 shRNA Plasmid (h) - sc-105008-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

3β-HSD2 shRNA (h) Lentiviral Particles - sc-105008-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU220251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10334 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10334 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03598 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03598

HSD3B2 siRNA (Human) - CRH2246 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSD3B2 - MBS8216067 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HSD3B2 (NM_000198.3) - SHH315293 from Creative biogene

Category siRNA
Species Reactivities Human

Human HSD3B2 siRNA - orb262748 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSD3B2 shRNA Plasmid (Human) - CHH2246 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HSD3B2 miRNA 3'UTR clone - MiUTR3H-13065 from Creative biogene

Species Reactivities Human

HSD3B2 miRNA 3'UTR clone - MiUTR3H-13066 from Creative biogene

Species Reactivities Human
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