Gene Symbol | HSD3B2 |
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Entrez Gene | 3284 |
Alt Symbol | HSD3B, HSDB, SDR11E2 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
Other Description | 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II|3-beta-HSD II|3-beta-HSD adrenal and gonadal type|3-beta-hydroxy-5-ene steroid dehydrogenase|3-beta-hydroxy-Delta(5)-steroid dehydrogenase|delta 5-delta 4-isomerase type II|progesterone reductase|short chain dehydrogenase/reductase family 11E, member 2 |
Swissprots | Q9UD08 Q6AI10 A2RRA5 Q53GD4 P26439 Q16010 Q99890 Q6LDB9 |
Accessions | AAA36014 AAC60599 AAC60600 AAD14930 AJF45348 EAW56700 EAW56701 EAW56702 P26439 AK222997 BAD96717 AK313413 BAG36207 AV705363 BC038419 AAH38419 BC131488 AAI31489 BP197992 CF596786 DQ891764 ABM82690 DQ894948 ABM85874 M67466 AAA36016 NM_000198 NP_000189 NM_001166120 NP_001159592 |
Function | 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. |
Tissue Specificity | Expressed in adrenal gland, testis and ovary. |
Top Pathways | Steroid hormone biosynthesis, Ovarian steroidogenesis |
Human HSD3B2 full length protein - ab114766 from Abcam
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Human HSD3B2 protein fragment - ab114767 from Abcam
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HSD3B2 Antibody Blocking Peptide - LS-E16249 from LifeSpan Bioscience
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Recombinant Human Beta Hydroxysteroid Dehydrogenase Protein - H00003284-P01 from Novus Biologicals
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Beta Hydroxysteroid Dehydrogenase Partial Recombinant Protein - H00003284-Q01 from Novus Biologicals
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HSD3B2-Antibody-C-term-Blocking-Peptide - BP18318b from Abgent, a WuXi AppTec company
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HSD3B2-Antibody-N-term-Blocking-Peptide - BP6761a from Abgent, a WuXi AppTec company
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HSD3B2 Blocking Peptide - 33R-3671 from Fitzgerald
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3-beta HSD2 / HSD3B2 - H00003284-P01-10 from Acris Antibodies
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3-beta HSD2 / HSD3B2 - H00003284-P01-25 from Acris Antibodies
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3-beta HSD2 / HSD3B2 - H00003284-Q01-10 from Acris Antibodies
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3-beta HSD2 / HSD3B2 - H00003284-Q01-25 from Acris Antibodies
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HSD3B2 fusion protein - ag7782 from Proteintech Group
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HSD3B2 fusion protein - ag4291 from Proteintech Group
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Recombinant Human HSD3B2 - HSD3B2-29343TH from Creative Biomart
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Recombinant Human HSD3B2 - HSD3B2-29345TH from Creative Biomart
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3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2), Recombinant Protein - MBS957764 from MyBioSource
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3-beta HSD2 / HSD3B2 - TP306593 from Acris Antibodies
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3-beta HSD2 / HSD3B2 (transcript variant 2) - TP328855 from Acris Antibodies
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HSD3B2 Blocking Peptide - abx061608 from Abbexa
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HSD3B2 Peptide, Human - M34GP07287H from Creative Peptides
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HSD3B2 Blocking Peptide - CBP5295 from Cohesion Biosciences
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3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2), Recombinant Protein - MBS7016797 from MyBioSource
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Recombinant Human HSD3B2 Protein, Myc/DDK-tagged - HSD3B2-001H from Creative Biomart
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Recombinant Human HSD3B2 Protein, Myc/DDK-tagged - HSD3B2-002H from Creative Biomart
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