APOBEC3H

Gene Symbol	APOBEC3H
Entrez Gene	164668
Alt Symbol	A3H, ARP-10, ARP10
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
Other Description	APOBEC-related protein 10|DNA dC->dU-editing enzyme APOBEC-3H
Swissprots	Q5JYL9 E9PF38 B7TQM5 B0QYP1 Q6NTF7 Q6IC87 B0QYP0
Accessions	ACJ60861 EAW60294 EAW60295 EAW60296 Q6NTF7 BC069023 AAH69023 BQ052182 BQ054330 BU585251 CR456481 CAG30367 FJ376611 ACK77772 FJ376612 ACK77773 FJ376613 ACK77774 FJ376614 ACK77775 FJ376615 ACK77776 FJ376616 ACK77777 FJ376617 ACK77778 KC329529 AGI04217 XM_011529990 XP_011528292 XM_011529991 XP_011528293 XM_011529992 XP_011528294 NM_001166002 NP_001159474 NM_001166003 NP_001159475 NM_001166004 NP_001159476 NM_181773 NP_861438
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. The A3H- var/haplotype 2 exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single- stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against T-cell leukemia virus type 1 (HTLV-1) and may inhibit th
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Haplotype 1 is distributed in both the nucleus and cytoplasm, whereas haplotype 2 is predominantly cytoplasmic.
Tissue Specificity	Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung, testis, ovary, fetal liver and skin. {ECO:0000269|PubMed:16571802, ECO:0000269|PubMed:20308164}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

APOBEC3H (FL-182) - sc-98334 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

APOBEC3H (S-12) - sc-86069 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

APOBEC3H (Y-17) - sc-86070 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-ARP10 antibody - ab73055 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-ARP10 antibody - C-terminal - ab135335 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ARP10 antibody - C-terminal - ab187112 from Abcam Host Rabbit Clonality Polyclonal

Anti-APOBEC3H Antibody (C-Terminus) - LS-C151868 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-APOBEC3H Antibody - LS-C306294 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

ARP10 Antibody - NBP1-91682 from Novus Biologicals Prices $129.00, $419.00 Sizes 25 µl, 100 µl Host Rabbit Clonality Polyclonal

ARP10 Antibody - H00164668-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-RP4-742C19.3 antibody produced in mouse - SAB1400833 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-APOBEC3H antibody produced in rabbit - HPA021492 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

APOBEC3H Antibody - C-terminal region (ARP65003_P050) - ARP65003_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti -APOBEC3H (Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3H,ARP10, DJ742C19.2) - 123419 from USBiological Life Science Host Mouse Clonality Polyclonal

APOBEC3H antibody - H00164668-B01P from Acris Antibodies Prices $360.00 Sizes 50 µg Host Mouse Clonality Polyclonal

APOBEC3H antibody - 17302-1-AP from Proteintech Group Host Rabbit Clonality Polyclonal

APOBEC3H, Polyclonal Antibody - MBS6000927 from MyBioSource Prices $580.00 Sizes 50 µg Host Mouse Clonality Polyclonal

APOBEC3H, Polyclonal Antibody - MBS2517581 from MyBioSource Prices $195.00, $270.00, $435.00 Sizes 60 µl, 120 µl, 200 µl Host Rabbit Clonality Polyclonal

APOBEC3H Antibody - EPP10476 from Elabscience Prices $296.00, $485.00 Sizes 120 μl, 200 μl Host Rabbit Clonality Polyclonal

Anti-APOBEC3H (aa 129-178) polyclonal antibody - DPABH-26006 from Creative Diagnostics Host Rabbit Clonality Polyclonal

Anti-APOBEC3H monoclonal antibody - DCABH-10559 from Creative Diagnostics Host Rabbit Clonality Monoclonal

APOBEC3H (C) Antibody, Rabbit Polyclonal - R1082-2 from Abiocode Prices $249.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

APOBEC3H antibody - TA337730 from Acris Antibodies Prices $325.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

APOBEC3H antibody - orb338241 from Biorbyt Prices $238.00, $281.00, $323.00 Sizes 20 μl (Trial Size), 50 μl, 100 μl Host Rabbit Clonality Polyclonal

APOBEC3H Antibody - 45925 from Signalway Antibody Prices $189.00, $279.00 Sizes 50 µl, 100 µl Host Rabbit Clonality Polyclonal

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