APOBEC3H

Gene Symbol APOBEC3H
Entrez Gene 164668
Alt Symbol A3H, ARP-10, ARP10
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
Other Description APOBEC-related protein 10|DNA dC->dU-editing enzyme APOBEC-3H
Swissprots Q5JYL9 E9PF38 B7TQM5 B0QYP1 Q6NTF7 Q6IC87 B0QYP0
Accessions ACJ60861 EAW60294 EAW60295 EAW60296 Q6NTF7 BC069023 AAH69023 BQ052182 BQ054330 BU585251 CR456481 CAG30367 FJ376611 ACK77772 FJ376612 ACK77773 FJ376613 ACK77774 FJ376614 ACK77775 FJ376615 ACK77776 FJ376616 ACK77777 FJ376617 ACK77778 KC329529 AGI04217 XM_011529990 XP_011528292 XM_011529991 XP_011528293 XM_011529992 XP_011528294 NM_001166002 NP_001159474 NM_001166003 NP_001159475 NM_001166004 NP_001159476 NM_181773 NP_861438
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. The A3H- var/haplotype 2 exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single- stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against T-cell leukemia virus type 1 (HTLV-1) and may inhibit th
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Haplotype 1 is distributed in both the nucleus and cytoplasm, whereas haplotype 2 is predominantly cytoplasmic.
Tissue Specificity Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung, testis, ovary, fetal liver and skin. {ECO:0000269|PubMed:16571802, ECO:0000269|PubMed:20308164}.

Human ARP10 full length protein - ab165769 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab165769 on a 12.5% SDS-PAGE stained with Coomassie Blue.

APOBEC3H Antibody Blocking Peptide - LS-E23683 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human ARP10 Protein - H00164668-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

APOBEC3H - H00164668-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

APOBEC3H - H00164668-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

APOBEC3H fusion protein - Ag11465 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

APOBEC3H fusion protein - ag11183 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human APOBEC3H, His-tagged - APOBEC3H-9758H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human DNA dC->dU-editing enzyme APOBEC-3H(APOBEC3H) - CSB-YP750736HU CSB-EP750736HU CSB-BP750736HU CSB-MP750736HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

ARP10 Recombinant Protein Antigen - NBP1-91682PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

APOBEC3H Peptide, Human - M34GP00780H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

DNA dC->dU-editing enzyme APOBEC-3H (APOBEC3H), Recombinant Protein - MBS1285683 from MyBioSource

Category Protein
Prices $950.00, $950.00, $1,170.00, $1,170.00, $1,415.00, $1,415.00, $1,880.00, $1,880.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

DNA dC->dU-editing enzyme APOBEC-3H (APOBEC3H), Recombinant Protein - MBS1411982 from MyBioSource

Category Protein
Prices $960.00, $960.00, $1,185.00, $1,185.00, $1,440.00, $1,440.00, $1,905.00, $1,905.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
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