REL

Gene Symbol	REL
Entrez Gene	5966
Alt Symbol	C-Rel
Species	Human
Gene Type	protein-coding
Description	v-rel avian reticuloendotheliosis viral oncogene homolog
Other Description	oncogene REL, avian reticuloendotheliosis|proto-oncogene c-Rel
Swissprots	Q17RU2 Q04864 Q6LDY0 Q2PNZ7
Accessions	AAA52073 ABC40747 CBX47437 EAX00028 Q04864 AA279919 AK123369 AK303926 BAG64854 BC051005 BC117191 AAI17192 BC143885 AAI43886 BG036646 BX111941 CN414487 HY123671 X75042 CAA52954 XM_011533010 XP_011531312 NM_001291746 NP_001278675 NM_002908 NP_002899
Function	Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an in
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	Viral carcinogenesis, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Phospho-REL / C-Rel (Ser503) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1613 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Human REL / C-Rel ELISA Kit (Cell-Based ELISA) - LS-F2283 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Rabbit anti-c-Rel Antibody, Affinity Purified - PLA0217 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Rel Colorimetric Cell-Based ELISA Kit - CB5603 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Rel (Phospho-Ser503) Colorimetric Cell-Based ELISA Kit - CBP1668 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

v-rel reticuloendotheliosis viral oncogene homolog (avian) , ELISA Kit - MBS9332004 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/ml Range 3.12 ng/ml - 100 ng/ml

Rel ELISA Kit - DEIA-XYA1551 from Creative Diagnostics Category ELISA Kit

Rel (Phospho-Ser503) ELISA Kit - DEIA-XYA1552 from Creative Diagnostics Category ELISA Kit

Turkey REL ELISA Kit - E095524 from Biobool Category ELISA Kit

Human REL ELISA Kit - E095523 from Biobool Category ELISA Kit

anti-c-Rel antibody - ARG55466 from Arigo Biolaboratories Category ELISA Kit

anti-c-Rel antibody - ARG55443 from Arigo Biolaboratories Category ELISA Kit

Rel Colorimetric Cell-Based ELISA Kit - EKA50518 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

Proto-Oncogene C-Rel (REL), ELISA Kit - MBS9397442 from MyBioSource Category ELISA Kit

Proto-Oncogene C-Rel (REL), ELISA Kit - MBS9397450 from MyBioSource Category ELISA Kit

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