REL

Gene Symbol REL
Entrez Gene 5966
Alt Symbol C-Rel
Species Human
Gene Type protein-coding
Description v-rel avian reticuloendotheliosis viral oncogene homolog
Other Description oncogene REL, avian reticuloendotheliosis|proto-oncogene c-Rel
Swissprots Q17RU2 Q04864 Q6LDY0 Q2PNZ7
Accessions AAA52073 ABC40747 CBX47437 EAX00028 Q04864 AA279919 AK123369 AK303926 BAG64854 BC051005 BC117191 AAI17192 BC143885 AAI43886 BG036646 BX111941 CN414487 HY123671 X75042 CAA52954 XM_011533010 XP_011531312 NM_001291746 NP_001278675 NM_002908 NP_002899
Function Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an in
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways Viral carcinogenesis, Transcriptional misregulation in cancer

c-Rel Antibody - 4727 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from K562, Raji and 293 cells, using c-Rel Antibody.

c-Rel (D5G1A) Rabbit mAb (ChIP Formulated) - 12659 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 immunoprecipitations)
Host Rabbit
Clonality Monoclonal
Clone D5G1A
Chromatin immunoprecipitations were performed with cross-linked chromatin from 4 x 10 6 Jurkat cells treated with TPA (12-O-Tetradecanoylphorbol-13-Acetate) #4174 (50ng/ml) and Ionomycin, Calcium Salt #9995 (200ng/ml) and either 5 μl of c-Rel (D5G1A) Rabbit mAb (ChIP Formulated) or 2 μl of Normal Rabbit IgG #2729 using SimpleChIP ® Enzymatic Chromatin IP Kit (Magnetic Beads) #9003. The enriched DNA was quantified by real-time PCR using human BCL2L1 promoter primers, SimpleChIP ® Human EP300 Promoter Primers #12281, and SimpleChIP ® Human α Satellite Repeat Primers #4486. The amount of immunoprecipitated DNA in each sample is represented as signal relative to the total amount of input chromatin, which is equivalent to one.

c-Rel (D4Y6M) Rabbit mAb - 12707 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4Y6M
Western blot analysis of extracts from various cell lines and tissues using c-Rel (D4Y6M) Rabbit mAb.

c-Rel (G57) Antibody - 4774 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

c-Rel (D-6) - sc-373713 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Rel (D-6): sc-373713. Western blot analysis of c-Rel expression in KNRK (A) and MM-142 (B) whole cell lysates.

c-Rel (C) - sc-71 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of c-Rel expression in RAW 264.7 (A) and MM-142 (B) whole cell lysates. Antibodies tested include c-Rel (C)-G: sc-71-G (A) and c-Rel (C): sc-71 (B).

c-Rel (G-7) - sc-365720 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Rel (G-7): sc-365720. Western blot analysis of c-Rel expression in SP2/0 whole cell lysate.

c-Rel (B-4) - sc-365694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Rel (B-4): sc-365694. Western blot analysis of c-Rel expression in SP2/0 whole cell lysate.

c-Rel (N-466) - sc-272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Rel (N-466): sc-272. Immunofluorescence staining of methanol-fixed KNRK cells showing cytoplasmic localization.

c-Rel (N) - sc-70 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Rel (N): sc-70. Western blot analysis of c-Rel expression in uninduced KNRK whole cell lysate.

c-Rel (B-6) - sc-6955 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Rel (B-6): sc-6955. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing cytoplasmic staining of follicle cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Anti-c-Rel (phospho S503) antibody - ab30624 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-c-Rel (phospho S503) antibody (ab30624) at 1/500 dilutionLane 1 : extracts from MDA-MB-435 cells (5-30ug).Lane 2 : extracts from MDA-MB-435 cells (5-30ug), preincubated with synthesized peptide (negative control).

Anti-c-Rel (phospho S503) antibody - ab131727 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-c-Rel (phospho S503) antibody - ab196003 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-c-Rel (phospho S503) antibody (ab196003) at 1/500 dilutionLane 1 : MDA-MB-435 whole cell lysate with antigen specific peptideLane 2 : MDA-MB-435 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-c-Rel antibody - ab129343 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab129343 at 2.5 µg/ml staining c-Rel in Formalin-Fixed, Paraffin-Embedded Human thymus tissue by immunohistochemistry.

Anti-c-Rel antibody - ab31413 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab31413 at 1/50, staining human c-Rel in paraffin embedded human breast carcinoma tissue using immunohistochemistry.

Anti-c-Rel antibody - ab7556 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-c-Rel antibody - ab99551 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-c-Rel antibody (ab99551) at 0.5 µg/ml (incubation time: 1 hour) + Human Spleen lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-c-Rel antibody - ab19464 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-c-Rel antibody [EPR2558] - ab108299 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2558
Anti-c-Rel antibody [EPR2558] (ab108299) at 1/1000 dilution (purified) + HuT-78 cell lysate at 10 µgSecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-c-Rel antibody [EPR2559(2)] - ab133251 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2559(2)
All lanes : Anti-c-Rel antibody [EPR2559(2)] (ab133251) at 1/10000 dilutionLane 1 : Daudi cell lysatesLane 2 : HuT-78 cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-c-Rel antibody - C-terminal - ab197915 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling c-Rel with ab197915 at 1/30 dilution.

Anti-c-Rel antibody - C-terminal - ab71210 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-c-Rel antibody - C-terminal (ab71210) at 1/100 dilutionLane 1 : Jurkat cell line lysateLane 2 : Mouse kidney lysateLysates/proteins at 12.5 µg per lane.

Anti-REL / C-Rel Antibody (C-Terminus) - LS-C37643 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-REL / C-Rel Antibody (C-Terminus) - LS-C37642 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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