REL

Gene Symbol	REL
Entrez Gene	5966
Alt Symbol	C-Rel
Species	Human
Gene Type	protein-coding
Description	v-rel avian reticuloendotheliosis viral oncogene homolog
Other Description	oncogene REL, avian reticuloendotheliosis|proto-oncogene c-Rel
Swissprots	Q17RU2 Q04864 Q6LDY0 Q2PNZ7
Accessions	AAA52073 ABC40747 CBX47437 EAX00028 Q04864 AA279919 AK123369 AK303926 BAG64854 BC051005 BC117191 AAI17192 BC143885 AAI43886 BG036646 BX111941 CN414487 HY123671 X75042 CAA52954 XM_011533010 XP_011531312 NM_001291746 NP_001278675 NM_002908 NP_002899
Function	Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an in
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	Viral carcinogenesis, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

c-Rel peptide - ab7557 from Abcam Category Peptide Prices $176.00 Sizes 50 µg

REL / C-Rel Antibody Blocking Peptide - LS-E10815 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

REL / C-Rel Antibody Blocking Peptide - LS-E8211 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

REL / C-Rel Antibody Blocking Peptide - LS-E27305 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

REL / C-Rel Antibody Blocking Peptide - LS-E13254 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

REL / C-Rel Antibody Blocking Peptide - LS-E13719 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

c-Rel Blocking Peptide - NB600-474PEP from Novus Biologicals Category Peptide Prices $169.00 Sizes 50 µg Species Human

c-Rel Peptide - P2000 from Novus Biologicals Category Peptide Species Human

C-rel-NFkB-Antibody-C-term-Blocking-Peptide - BP6336c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

c-Rel blocking peptide - GTX88187-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

c-Rel peptide - GTX27557 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg

Human REL protein - orb245687 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

REL Immunizing peptide - orb17800 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

c-Rel Blocking Peptide - abx063189 from Abbexa Category Peptide Species Human, Mouse, Rat

c-Rel Peptide - AC21-2127-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

REL control peptide - R1010CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

REL Peptide - 42-533P from ProSci Category Peptide Species Human

Recombinant V-Rel Reticuloendotheliosis Viral Oncogene Homolog (REL) - RPP741Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

c-Rel Blocking Peptide - CBP1995 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

c-Rel (N497) Peptide - BS1314P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p-c-Rel (S503) Peptide - BS4839P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant human Proto-oncogene c-Rel protein - CSB-EP178194h CSB-BP178194h CSB-MP178194h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Proto-oncogene c-Rel(REL),partial - CSB-RP178194h from Cusabio Category Protein Source E.coli Species Human

c-Rel (1-300) - sc-4030 from Santa Cruz Biotechnology Category Protein Prices $167.00 Sizes 50 µg Species Human

Proto-oncogene c-Rel protein - RPC141089 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

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