RAB1A

Gene Symbol	RAB1A
Entrez Gene	5861
Alt Symbol	RAB1, YPT1
Species	Human
Gene Type	protein-coding
Description	RAB1A, member RAS oncogene family
Other Description	GTP binding protein Rab1a|RAB1, member RAS oncogene family|Rab GTPase YPT1 homolog|YPT1-related protein|ras-related protein Rab-1A
Swissprots	P62820 Q6FIE7
Accessions	AAK94463 EAW99917 EAW99918 EAW99919 EAW99920 EAW99921 EAW99922 EAW99923 EAW99924 EAW99925 P62820 AF498929 AAM21077 AI768809 AK055927 BAB71048 AK303678 BAH14013 AK315495 BAG37879 AL050268 CAB43369 AM392684 CAL37562 BC000905 AAH00905 BG704216 BT019528 AAV38335 BT019529 AAV38336 BX571747 CAE11872 CR533479 CAG38510 CR536488 CAG38727 DC352417 DQ894084 ABM85010 EU831590 ACE87190 EU831675 ACE86509 M28209 AAA60240 X13898 CAA32098 XM_005264468 XP_005264525 XM_011533009 XP_011531311 NM_004161 NP_004152 NM_015543 NP_056358
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport. {ECO:0000269|PubMed:20639577, ECO:0000269|PubMed:20861236, ECO:0000269|P
Subcellular Location	Golgi apparatus. Endoplasmic reticulum. Early endosome. Cytoplasm, cytosol. Membrane. Melanosome {ECO:0000250}. Note=Alternates between membrane-associated and cytosolic forms.
Top Pathways	Legionellosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAB1A ELISA Kit (Sandwich ELISA) - LS-F8928 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 0.156-10 ng/ml

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS061961 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS054295 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS108337 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS080964 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS080468 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS066478 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family, ELISA Kit - MBS089317 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, member RAS oncogene family, ELISA Kit - MBS9331944 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAB1A, Member RAS Oncogene Family (RAB1A), ELISA Kit - MBS2024283 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human RAB1A is typically less than 0.067ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

ELISA Kit for RAB1A, Member RAS Oncogene Family (RAB1A) - SEJ783Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.067ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

CLIA Kit for RAB1A, Member RAS Oncogene Family (RAB1A) - SCJ783Hu from Uscn Life Science Inc. Category CLIA Kit Sensitivity The minimum detectable dose of this kit is typically less than 5.27pg/mL. Range 13.72-10000pg/mL The standard curve concentrations used for the CLIA’s were 10000pg/mL, 3333.33pg/mL, 1111.11pg/mL, 370.37pg/mL, 123.46pg/mL, 41.15pg/mL, 13.72pg/mL

ELISA Kit for RAB1A, Member RAS Oncogene Family (RAB1A) - SEJ783Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human RAB1A, Member RAS Oncogene Family (RAB1A) ELISA Kit - EKU07000 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.067 ng/mL Range 0.156-10 ng/mL

CLIA Kit for RAB1A, Member RAS Oncogene Family (RAB1A) - CKU72609 from Biomatik Category CLIA Kit Prices $882.00 Sizes 96 t Sensitivity The limit of detection is typically less than 0.055ng/mL Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human RAB1A ELISA Kit - abx152910 from Abbexa Category ELISA Kit Sensitivity 0.067 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human RAB1A, Member RAS Oncogene Family CLIA Kit - abx190393 from Abbexa Category CLIA Kit Range 13.72 pg/ml - 10000 pg/ml

RAB1A, Member RAS Oncogene Family (RAB1A), ELISA Kit - MBS2025491 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of RAB1A is typically less than 0.054ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

RAB1A, Member RAS Oncogene Family (RAB1A), CLIA Kit - MBS2000510 from MyBioSource Category CLIA Kit Prices $440.00, $655.00, $900.00, $3,705.00, $6,680.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of this kit is typically less than 5.27pg/mL. Range 13.72-10000pg/mL

Rat RAB1A ELISA Kit (Sandwich ELISA) - LS-F25562 from LifeSpan Bioscience Category ELISA Kit Prices $840.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Human RAB1A ELISA Kit - orb370425 from Biorbyt Category ELISA Kit Prices $553.00, $621.00 Sizes 48 test, 96 test Range Detection Range: 0.156-10ng/mL Detection low threshold: 0.067ng/mL

Human RAB1A ELISA Kit (CLIA) - LS-F26577 from LifeSpan Bioscience Category ELISA Kit Prices $930.00 Sizes 1 plate Sensitivity 5.27 pg/ml Range 0.156-10 ng/ml

Human RAB1A ELISA Kit - abx571592 from Abbexa Category ELISA Kit Sensitivity 0.067 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human RAB1A, Member RAS Oncogene Family (RAB1A) ELISA Kit (CLIA) - EKU72609 from Biomatik Category ELISA Kit Prices $882.00, $3,880.80, $7,056.00 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 5.27pg/mL Range 13.72-10000pg/mL The standard curve concentrations used for the CLIA’s were 10000pg/mL, 3333.33pg/mL, 1111.11pg/mL, 370.37pg/mL, 123.46pg/mL, 41.15pg/mL, 13.72pg/mL

Human RAB1A, Member RAS Oncogene Family (RAB1A) CLIA Kit - EKU10016 from Biomatik Category CLIA Kit Prices $882.00, $3,881.00, $7,056.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 5.27 pg/mL Range 156.25-10000 pg/mL

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