RAB1A

Gene Symbol RAB1A
Entrez Gene 5861
Alt Symbol RAB1, YPT1
Species Human
Gene Type protein-coding
Description RAB1A, member RAS oncogene family
Other Description GTP binding protein Rab1a|RAB1, member RAS oncogene family|Rab GTPase YPT1 homolog|YPT1-related protein|ras-related protein Rab-1A
Swissprots P62820 Q6FIE7
Accessions AAK94463 EAW99917 EAW99918 EAW99919 EAW99920 EAW99921 EAW99922 EAW99923 EAW99924 EAW99925 P62820 AF498929 AAM21077 AI768809 AK055927 BAB71048 AK303678 BAH14013 AK315495 BAG37879 AL050268 CAB43369 AM392684 CAL37562 BC000905 AAH00905 BG704216 BT019528 AAV38335 BT019529 AAV38336 BX571747 CAE11872 CR533479 CAG38510 CR536488 CAG38727 DC352417 DQ894084 ABM85010 EU831590 ACE87190 EU831675 ACE86509 M28209 AAA60240 X13898 CAA32098 XM_005264468 XP_005264525 XM_011533009 XP_011531311 NM_004161 NP_004152 NM_015543 NP_056358
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport. {ECO:0000269|PubMed:20639577, ECO:0000269|PubMed:20861236, ECO:0000269|P
Subcellular Location Golgi apparatus. Endoplasmic reticulum. Early endosome. Cytoplasm, cytosol. Membrane. Melanosome {ECO:0000250}. Note=Alternates between membrane-associated and cytosolic forms.
Top Pathways Legionellosis

Rab1A (D5F8M) Rabbit mAb - 13099 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5F8M
Western blot analysis of extracts from various cell lines using Rab1A (D5F8M) Rabbit mAb.

Rab1A (D3X9S) Rabbit mAb - 13075 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3X9S
Western blot analysis of extracts from various cell lines using Rab1A (D3X9S) Rabbit mAb.

Rab 1 (FL-205) - sc-28566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rab 1 (FL-205): sc-28566. Western blot analysis of Rab 1 expression in human platelet extract (A) and JEG-3 (B) whole cell lysate.

Rab 1A (G-10) - sc-377201 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rab 1A (G-10): sc-377201. Western blot analysis of Rab 1A expression in rat eye tissue extract.

Rab 1A (C-19) - sc-311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rab 1A (C-19): sc-311. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse eye tissue showing cytoplasmic localization.

Rab 1A (P-13) - sc-26541 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Rab 1A (G-19) - sc-26543 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rab 1A (G-19): sc-26543. Western blot analysis of Rab 1A expression in non-transfected: sc-117752 (A) and mouse Rab 1A transfected: sc-125876 (B) 293T whole cell lysates.

Anti-Rab1A antibody - ab104604 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab104604 stained A549 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab104604 at 1µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Rab1A antibody - ab124357 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab124357, at 1/100 dilution, staining Rab1A in Formalin-fixed, Paraffin-embedded Human Fetal Colon tissue by Immunohistochemistry.

Anti-RAB1A Antibody (Biotin) - LS-C183270 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB1A Antibody (FITC) - LS-C183271 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB1A Antibody (HRP) - LS-C183272 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB1A Antibody - LS-C190019 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-RAB1A Antibody (clone 3F10) - LS-C198043 from LifeSpan Bioscience

Prices $355.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3F10

Anti-RAB1A Antibody (aa1-204) - LS-C178907 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RAB1A Antibody (Biotin) - LS-C210953 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Ras-related protein Rab-1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 22.5 kDa. Observed band size: 80 kDa.

Anti-RAB1A Antibody (C-Terminus) - LS-C107582 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RAB1A antibody LS-C107582 Western blot of Fetal Muscle lysate.

Anti-RAB1A Antibody - LS-C210951 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Ras-related protein Rab-1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 22.5 kDa. Observed band size: 80 kDa.

Anti-RAB1A Antibody (FITC) - LS-C210954 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Ras-related protein Rab-1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 22.5 kDa. Observed band size: 80 kDa.

Anti-RAB1A Antibody (HRP) - LS-C210952 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Ras-related protein Rab-1A antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 22.5 kDa. Observed band size: 80 kDa.

Anti-RAB1A Antibody (C-Terminus) IHC-plus™ - LS-B9788 from LifeSpan Bioscience

Prices $395.00
Sizes 300 µg
Host Goat
Clonality Polyclonal
Anti-RAB1A / RAB1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Rab1A Antibody - NBP1-55113 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Rab1A Antibody [NBP1-55113] - Reccomended Titration: 0.2 - 1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Muscle

Rab1A Antibody - NBP2-20037 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Rab1A Antibody [NBP2-20037] - Western Blot analysis of RAB1A expression in transfected 293T cell line by RAB1A polyclonal antibody. A: Non-transfected lysate. B: RAB1A transfected lysate. 12% SDS PAGE gel, diluted at 1:500.

Rab1A Antibody (3F10) - H00005861-M07A from Novus Biologicals

Prices $359.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3F10

Monoclonal Anti-RAB1A, (C-terminal) antibody produced in mouse - SAB1402889 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3F10
<B>Immunoblotting</B><BR/>Monoclonal Anti-RAB1A: <B>Cat. No. SAB1402889</B>: Antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.
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