CLSTN3

Gene Symbol	CLSTN3
Entrez Gene	9746
Alt Symbol	CDHR14, CSTN3, alcbeta
Species	Human
Gene Type	protein-coding
Description	calsyntenin 3
Other Description	alc-beta\|alcadein beta\|alcadein-beta\|cadherin-related family member 14\|calsyntenin-3
Swissprots	D3DUT6 O94831 Q9BQT9 Q2T9J5 Q5UE57
Accessions	EAW88676 EAW88677 EAW88678 EAW88679 EAW88680 Q9BQT9 AA864252 AB018269 BAA34446 AJ277460 CAC33084 AK299177 BAG61223 AK299246 BAG61277 AK316059 BAH14430 AY753302 AAV30552 BC039075 AAH39075 BC104767 AAI04768 BC111491 AAI11492 BC112283 AAI12284 BC148258 AAI48259 DA092023 XM_006719163 XP_006719226 NM_014718 NP_055533
Function	May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization. {ECO:0000250}.
Tissue Specificity	According to PubMed:12498782, expressed predominantly in the brain and in kidney. Low levels in heart, skeletal muscle, liver, placenta, pancreas and lung. According to PubMed:12972431, predominant expression in brain, and only marginal in kidney. In brain, present throughout all cortical layers, highest levels in GABAergic neurons (based on morphology and distribution pattern). {ECO:0000269\|PubMed:12498782, ECO:0000269\|PubMed:12972431}.

calsyntenin-3 (D-16) - sc-133316 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

calsyntenin-3 (D-16): sc-133316. Western blot analysis of calsyntenin-3 expression in WI 38 whole cell lysate.

calsyntenin-3 (E-14) - sc-133317 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

calsyntenin-3 (E-14): sc-133317. Western blot analysis of calsyntenin-3 expression in mouse pancreas tissue extract.

Anti-CLSTN3 antibody - ab101955 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CLSTN3 antibody (ab101955) at 1 µg/ml + RPMI-8226 cell lysate at 10 µgdeveloped using the ECL technique

Anti-CLSTN3 Antibody (aa179-228) - LS-C116335 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CLSTN3 antibody LS-C116335 Western blot of RPMI-8226 cell lysate.

Calsyntenin-3 Antibody - AF5244 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep
Clonality	Polyclonal

Calsyntenin‑3 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Sheep Anti-Human Calsyntenin‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5244) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). Specific labeling was localized to the neuronal processes and synaptic boutons. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Calsyntenin-3 Antibody - NBP1-59713 from Novus Biologicals

Prices	$369.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: Calsyntenin-3 Antibody [NBP1-59713] - Titration: 0.2-1 ug/ml, Positive Control: RPMI 8226 cell lysate.

Calsyntenin-3 Antibody - NBP2-13846 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: Calsyntenin-3 Antibody [NBP2-13846] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and Leydig cells.

Anti-CLSTN3 antibody produced in rabbit - HPA046913 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-CLSTN3:<B>Cat. No. HPA046913</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and Leydig cells.

Anti-CLSTN3, (N-terminal) antibody produced in rabbit - SAB2105683 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-CLSTN3 (N-Terminal): <B>Cat. No. SAB2105683</B>: CLSTN3 in RPMI-8226 cell lysates with CLSTN3 antibody at 1.0 μg/mL.

CLSTN3 antibody - N-terminal region (ARP47060_P050) - ARP47060_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CLSTN3 antibody, N-term - GTX46369 from GeneTex

Prices	$319.00
Sizes	50 μg
Host	Rabbit
Clonality	Polyclonal

Anti-CLSTN3 antibody, N-term used in Western blot. GTX46369

Human Calsyntenin-3 Antibody - AF5244 from R&D Systems

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Sheep

Calsyntenin‑3 in Human Brain. Calsyntenin‑3 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Sheep Anti-Human Calsyntenin‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5244) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013 ). Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019 ) and counterstained with hematoxylin (blue). Specific labeling was localized to the neuronal processes and synaptic boutons. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections .

Human Calsyntenin-3 Affinity Purified Polyclonal Ab, Sheep IgG - AF5244-SP from R&D Systems

Host	Sheep
Clonality	Polyclonal

Calsyntenin 3 antibody - 70R-6618 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CLSTN3 antibody - 13302-1-AP from Proteintech Group

Host	Rabbit
Clonality	Polyclonal

CLSTN3, Polyclonal Antibody - MBS2518492 from MyBioSource

Prices	$195.00, $270.00, $435.00
Sizes	60 µl, 120 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

CLSTN3 Antibody - GWB-MQ648I from Genway Biotech

Prices	$368.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CLSTN3 Antibody - EPP11660 from Elabscience

Prices	$296.00, $485.00
Sizes	120 μl, 200 μl
Host	Rabbit
Clonality	Polyclonal

Anti-CLSTN3 monoclonal antibody - DCABH-15015 from Creative Diagnostics

Host	Rabbit
Clonality	Monoclonal

CLSTN3-antibody-N-terminal-region-AI12745 - AI12745 from Abgent, a WuXi AppTec company

Prices	$293.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

WB Suggested Anti-CLSTN3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: RPMI 8226 cell lysate

Calsyntenin 3, Polyclonal Antibody - MBS5302639 from MyBioSource

Prices	$455.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Calsyntenin-3 antibody - TA341951 from Acris Antibodies

Prices	$325.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CLSTN3 Antibody - abx145403 from Abbexa

Host	Rabbit
Clonality	Polyclonal

Anti-CLSTN3 (aa 179-228) polyclonal antibody - CABT-BL4397 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

Anti-CLSTN3 Antibody A09830 - A09830 from Boster Bio

Prices	$299.00
Sizes	1
Host	Rabbit
Clonality	Polyclonal

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