Gene Symbol | SLC17A6 |
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Entrez Gene | 57084 |
Alt Symbol | DNPI, VGLUT2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 17 (vesicular glutamate transporter), member 6 |
Other Description | differentiation-associated BNPI|differentiation-associated Na(+)-dependent inorganic phosphate cotransporter|differentiation-associated Na-dependent inorganic phosphate cotransporter|solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6|solute carrier family 17 member 6|vesicular glutamate transporter 2 |
Swissprots | Q9P2U8 A6NKS2 |
Accessions | CCO13815 CCQ43632 EAW68324 Q9P2U8 AB032435 BAA92874 AK294502 BAG57719 AK309131 BC069629 AAH69629 BC069640 AAH69640 BC069646 AAH69646 BQ185289 BQ188116 CK823303 DA392769 NM_020346 NP_065079 |
Function | Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. {ECO:0000269|PubMed:10820226, ECO:0000269|PubMed:11698620}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell junction, synapse, synaptosome {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, putamen, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus. {ECO:0000269|PubMed:10820226}. |
Top Pathways | Synaptic vesicle cycle, Glutamatergic synapse, Nicotine addiction, Retrograde endocannabinoid signaling |
VGLUT2 (D4E3U) Rabbit mAb - 14487 from Cell Signaling Technology
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VGLUT2 Antibody - 12937 from Cell Signaling Technology
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VGLUT2 (K-18) - sc-26027 from Santa Cruz Biotechnology
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VGLUT2 (N-12) - sc-26026 from Santa Cruz Biotechnology
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Anti-VGLUT2 antibody - ab101760 from Abcam
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Anti-VGLUT2 antibody - ab101756 from Abcam
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Anti-VGLUT2 antibody - ab84103 from Abcam
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Anti-VGLUT2 antibody - ab101759 from Abcam
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Anti-VGLUT2 antibody [S29-29] - ab134290 from Abcam
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Anti-VGLUT2 antibody - C-terminal - ab181773 from Abcam
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Anti-SLC17A6 / VGLUT2 Antibody (aa574-607) - LS-C344637 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (N-Terminus) - LS-C15455 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa265-315) - LS-C95235 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (clone S29-29) - LS-C150470 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (C-Terminus) - LS-C153594 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (clone 13A229) - LS-C183416 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 390) - LS-C231640 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 488) - LS-C231641 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 565) - LS-C231642 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 594) - LS-C231643 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 633) - LS-C231644 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 655) - LS-C231645 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 680) - LS-C231646 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, Atto 700) - LS-C231647 from LifeSpan Bioscience
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Anti-SLC17A6 / VGLUT2 Antibody (aa501-582, clone S29-29, AP) - LS-C231648 from LifeSpan Bioscience
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