Gene Symbol | SSTR5 |
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Entrez Gene | 6755 |
Alt Symbol | SS-5-R |
Species | Human |
Gene Type | protein-coding |
Description | somatostatin receptor 5 |
Other Description | somatostatin receptor subtype 5|somatostatin receptor type 5 |
Swissprots | P35346 Q9UJI5 P34988 Q541E0 |
Accessions | AAA20828 AAB31829 AAD38178 AAK61266 AAL88744 AAN86611 BAA04107 CBE74695 CDM63488 EAW85687 P35346 AK308381 BC141553 AAI41554 BC146576 AAI46577 DB202230 DQ448303 ABE27002 DQ448304 ABE27003 DW447547 XM_006720936 XP_006720999 NM_001053 NP_001044 NM_001172560 NP_001166031 NM_001172572 NM_001172573 |
Function | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization. {ECO:0000269|PubMed:12072395, ECO:0000269|PubMed:7908405, ECO:0000269|PubMed:8078491, ECO:0000269|PubMed:8373420}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. {ECO:0000269|PubMed:12072395, ECO:0000269|PubMed:7908405, ECO:0000269|PubMed:8078491}. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
Human Somatostatin Receptor 5 full length protein - ab152710 from Abcam
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Somatostatin Receptor 5 peptide - ab178801 from Abcam
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SSTR5 Antibody Blocking Peptide - LS-E6315 from LifeSpan Bioscience
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SSTR5 Antibody Blocking Peptide - LS-E28957 from LifeSpan Bioscience
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SSTR5 Antibody Blocking Peptide - LS-E28582 from LifeSpan Bioscience
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SSTR5 Antibody Blocking Peptide - LS-E28583 from LifeSpan Bioscience
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Somatostatin R5/SSTR5 Recombinant Protein - H00006755-P01 from Novus Biologicals
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SSTR5-Antibody-C-term-Blocking-Peptide - BP19004b from Abgent, a WuXi AppTec company
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SSTR5 Blocking Peptide - 33R-7415 from Fitzgerald
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SSTR5 - H00006755-G01 from Acris Antibodies
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SSTR5 - H00006755-P01-10 from Acris Antibodies
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SSTR5 - H00006755-P01-25 from Acris Antibodies
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SSTR5 fusion protein - ag18615 from Proteintech Group
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SSTR5 fusion protein - ag19408 from Proteintech Group
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SSTR5 fusion protein - Ag0519 from Proteintech Group
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Recombinant Human SSTR5, GST-tagged - SSTR5-2972H from Creative Biomart
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ChemiSCREEN™ Membrane Preparation Recombinant Human sst5 Somatostatin Receptor - HTS139M from EMD Millipore
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Recombinant Human Somatostatin R5/SSTR5 Protein - H00006755-G01 from Novus Biologicals
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Somatostatin Analog [D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2], Peptide - MBS659776 from MyBioSource
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SSTR5 Peptide, Human - M34GP15217H from Creative Peptides
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SSTR5 peptide - orb73236 from Biorbyt
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Somatostatin R5/SSTR5 Recombinant Protein Antigen - NBP2-56513PEP from Novus Biologicals
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Somatostatin receptor type 5 (SSTR5), Recombinant Protein - MBS7030539 from MyBioSource
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Somatostatin receptor type 5 (SSTR5), Recombinant Protein - MBS717765 from MyBioSource
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