SSTR5

Gene Symbol SSTR5
Entrez Gene 6755
Alt Symbol SS-5-R
Species Human
Gene Type protein-coding
Description somatostatin receptor 5
Other Description somatostatin receptor subtype 5|somatostatin receptor type 5
Swissprots P35346 Q9UJI5 P34988 Q541E0
Accessions AAA20828 AAB31829 AAD38178 AAK61266 AAL88744 AAN86611 BAA04107 CBE74695 CDM63488 EAW85687 P35346 AK308381 BC141553 AAI41554 BC146576 AAI46577 DB202230 DQ448303 ABE27002 DQ448304 ABE27003 DW447547 XM_006720936 XP_006720999 NM_001053 NP_001044 NM_001172560 NP_001166031 NM_001172572 NM_001172573
Function Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization. {ECO:0000269|PubMed:12072395, ECO:0000269|PubMed:7908405, ECO:0000269|PubMed:8078491, ECO:0000269|PubMed:8373420}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. {ECO:0000269|PubMed:12072395, ECO:0000269|PubMed:7908405, ECO:0000269|PubMed:8078491}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

SSTR5 (H-54) - sc-25679 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SSTR5 (H-54): sc-25679. Western blot analysis of SSTR5 expression in non-transfected 293T: sc-117752 (A), human SSTR5 transfected 293T: sc-129855 (B) and HeLa (C) whole cell lysates.

SSTR5 (C-15) - sc-11623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SSTR5 (C-15): sc-11623. Western blot analysis of human recombinant SSTR5 fusion protein.

Anti-Somatostatin Receptor 5 antibody - ab28618 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Somatostatin Receptor 5 antibody (ab28618) at 1 µg/ml + Brain: pituitary gland (Human) Whole Cell Lysate - adult normal tissue (ab29749) at 10 µgSecondaryGoat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.Observed band size : 42 kDa (why is the actual band size different from the predicted?)Additional bands at : 15 kDa,20 kDa,73 kDa. We are unsure as to the identity of these extra bands.Exposure time : 8 minutesSomatostatin Receptor 5 contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.

Anti-Somatostatin Receptor 5 antibody - ab198879 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Somatostatin Receptor 5 antibody (ab198879) at 1/350 dilution + Mouse thymus tissue lysate at 60 µgdeveloped using the ECL technique

Anti-Somatostatin Receptor 5 antibody [EPR7243] - ab156864 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7243
All lanes : Anti-Somatostatin Receptor 5 antibody [EPR7243] (ab156864) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : Human kidney lysateLane 3 : Human fetal liver lysateLane 4 : Human spleen lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Somatostatin Receptor 5 antibody [UMB4] - ab109495 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone UMB4
ICC/IF image of ab109495 stained Panc-1 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab109495 at 10µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 goat anti- rabbit (ab150081) IgG (H+L) preadsorbed, used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-Somatostatin Receptor 5 antibody - C-terminal - ab138863 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Somatostatin Receptor 5 antibody - C-terminal (ab138863) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-Somatostatin Receptor 5 antibody - Extracellular domain - ab140922 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labelling Somatostatin Receptor 5 with ab140922 at 10 µg/ml.

Anti-SSTR5 Antibody - LS-C75924 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SSTR5 Antibody - LS-C152840 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339, AP) - LS-C270448 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339, APC) - LS-C270449 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339, Biotin) - LS-C270450 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339, FITC) - LS-C270451 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339, Azide-free, HRP) - LS-C270452 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339, PE) - LS-C270456 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa311-339) - LS-C325403 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSTR5 Antibody (aa300-350) - LS-C47288 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot ofSSTR5 in human pancreas cell lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 0.25 ug/ml.

Anti-SSTR5 Antibody (aa311-339) - LS-C157097 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SSTR5 Antibody western blot of CEM cell line lysates (35 ug/lane). The SSTR5 antibody detected the SSTR5 protein (arrow).

Anti-SSTR5 Antibody - LS-C332381 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse thymus, using SSTR5 antibody.

Anti-SSTR5 Antibody (C-Terminus) IHC-plus™ - LS-A4419 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SSTR5 antibody LS-A4419 IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SSTR5 Antibody (C-Terminus) IHC-plus™ - LS-A2639 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SSTR5 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SSTR5 Antibody (Extracellular Domain) IHC-plus™ - LS-A2637 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SSTR5 antibody LS-A2637 IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Somatostatin R5/SSTR5 Antibody - NB100-56498 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-56498] - Analysis of Somatostatin R5/SSTR5 in human pancreas lysate in the 1) absence and 2) presence of immunizing peptide using Somatostatin Receptor 5 antibody at 0.25 ug/ml.

Somatostatin R5/SSTR5 Antibody (394401) [Unconjugated] - MAB4448 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 394401
HEK293 human embryonic kidney cell line transfected with either (A) human Somatostatin R5/SSTR5 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Somatostatin R5/SSTR5 Monoclonal Antibody (Catalog # MAB4448) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). Quadrant markers were set based on control antibody staining (Catalog # MAB002). View our protocol for Staining Membrane-associated Proteins.
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