Gene Symbol | RPAP2 |
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Entrez Gene | 79871 |
Alt Symbol | C1orf82, Rtr1 |
Species | Human |
Gene Type | protein-coding |
Description | RNA polymerase II associated protein 2 |
Other Description | RNA polymerase II-associated protein 2|putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 |
Swissprots | Q8IXW5 Q49AS7 C9JKB5 Q9H8Y2 |
Accessions | EAW73095 EAW73096 Q8IXW5 AI612918 AK023212 BAB14465 AK225054 BC031070 AAH31070 BC039014 AAH39014 JF432356 ADZ15573 XM_005271223 XP_005271280 XM_006710905 XP_006710968 XM_011542167 XP_011540469 XM_011542168 XP_011540470 XR_246295 NM_024813 NP_079089 |
Function | Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes. {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:22137580}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:22137580}. Nucleus {ECO:0000269|PubMed:22137580}. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner. |
RPAP2 (F-16) - sc-139547 from Santa Cruz Biotechnology
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Anti-RPAP2 antibody - ab110460 from Abcam
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RPAP2 Antibody - NBP2-13248 from Novus Biologicals
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Anti-RPAP2 (466-480) antibody produced in rabbit - SAB1102245 from Sigma-Aldrich
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Anti-RPAP2 antibody produced in rabbit - HPA046443 from Sigma-Aldrich
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RPAP2 Antibody (OAAF04215) - OAAF04215 from Aviva Systems Biology
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RPAP2 antibody - 70R-19952 from Fitzgerald
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RPAP2 Polyclonal Antibody - A4986 from ABclonal
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RPAP2 Antibody - abx003802 from Abbexa
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RPAP2 antibody - 17401-1-AP from Acris Antibodies
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RPAP2 antibody - H00079871-B01P from Acris Antibodies
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Anti-RPAP2, Polyclonal Antibody - 25-A4986 from ARP American Research Products
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Anti-RPAP2 antibody - STJ95537 from St John's Laboratory Ltd
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RPAP2 antibody - STJ27004 from St John's Laboratory Ltd
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RPAP2 antibody - 17401-1-AP from Proteintech Group
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RPAP2 - A4986 from NeoScientific
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RPAP2 Antibody - E11-18453C from Enogene
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RPAP2 Antibody - C18453 from Assay Biotechnology
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RNA polymerase II associated protein 2 , Polyclonal Antibody - MBS711590 from MyBioSource
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RPAP2 - MBS9125076 from MyBioSource
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RPAP2 Antibody - A01P0471 from BlueGene Biotech |
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RPAP2 (N-17) - sc-139545 from Santa Cruz Biotechnology
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RPAP2 Antibody - DF4445 from Affinity Biosciences
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RPAP2 Polyclonal Antibody - ENT4172 from Elabscience
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RPAP2 Antibody - CSB-PA004025 from Cusabio
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