Gene Symbol | RPAP2 |
---|---|
Entrez Gene | 79871 |
Alt Symbol | C1orf82, Rtr1 |
Species | Human |
Gene Type | protein-coding |
Description | RNA polymerase II associated protein 2 |
Other Description | RNA polymerase II-associated protein 2|putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 |
Swissprots | Q8IXW5 Q49AS7 C9JKB5 Q9H8Y2 |
Accessions | EAW73095 EAW73096 Q8IXW5 AI612918 AK023212 BAB14465 AK225054 BC031070 AAH31070 BC039014 AAH39014 JF432356 ADZ15573 XM_005271223 XP_005271280 XM_006710905 XP_006710968 XM_011542167 XP_011540469 XM_011542168 XP_011540470 XR_246295 NM_024813 NP_079089 |
Function | Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes. {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:22137580}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:22137580}. Nucleus {ECO:0000269|PubMed:22137580}. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner. |
RPAP2 fusion protein - Ag11374 from Proteintech Group
|
||||||||||
RPAP2 fusion protein - Ag11342 from Proteintech Group
|
||||||||||
Recombinant Human RPAP2, GST-tagged - RPAP2-2369H from Creative Biomart
|
||||||||||
Recombinant Human Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2(RP - CSB-YP816906HU CSB-EP816906HU CSB-BP816906HU CSB-MP816906HU from Cusabio
|
||||||||||
RPAP2 Recombinant Protein Antigen - NBP2-13248PEP from Novus Biologicals
|
||||||||||
RPAP2 Peptide, Human - M34GP13485H from Creative Peptides
|
||||||||||
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (RPAP2), Recombinant Protein - MBS1360390 from MyBioSource
|