SPRY1

Gene Symbol SPRY1
Entrez Gene 10252
Alt Symbol hSPRY1
Species Human
Gene Type protein-coding
Description sprouty homolog 1, antagonist of FGF signaling (Drosophila)
Other Description protein sprouty homolog 1|sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling)|spry-1
Swissprots D3DNX6 Q6PNE0 O43609
Accessions CBX47508 CBX47509 EAX05209 EAX05210 EAX05211 O43609 AF041037 AAC39566 AK026960 AL602431 AV692593 AY192146 AAP20102 AY590694 AAT06102 BC063856 AAH63856 CA447611 CN302060 DA765300 DB250100 HQ447467 ADQ31953 XM_005262686 XP_005262743 NM_001258038 NP_001244967 NM_001258039 NP_001244968 NM_005841 NP_005832 NM_199327 NP_955359
Function May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Subcellular Location Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
Top Pathways Jak-STAT signaling pathway

Spry1 (D9V6P) Rabbit mAb - 13013 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9V6P
Western blot analysis of extracts from various cell lines using Spry1 (D9V6P) Rabbit mAb.

Spry1 (D9V6I) Rabbit mAb - 12993 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9V6I
Western blot analysis of extracts from various cell lines using Spry1 (D9V6I) Rabbit mAb.

Spry1 Antibody - 8775 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Sprouty 1 (H-2) - sc-365520 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sprouty 1 (H-2): sc-365520. Western blot analysis of Sprouty 1 expression in Hep G2 whole cell lysate.

Sprouty 1 (H-120) - sc-30048 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Sprouty 1 (H-120): sc-30048. Western blot analysis of Sprouty 1 expression in non-transfected: sc-117752 (A) and human Sprouty 1 transfected: sc-117290 (B) 293T whole cell lysates.

Sprouty 1 (C-12) - sc-18599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Sprouty 1 (M-12) - sc-31108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Sprouty 1 (RR-15) - sc-100861 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Sprouty 1 (RR-15): sc-100861. Western blot analysis of Sprouty 1 expression in Hep G2 whole cell lysate.

Anti-Sprouty 1 antibody - ab111523 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Sprouty 1 antibody (ab111523) at 1 µg/mlLane 1 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 2 : Liver (Human) Tissue Lysate - fetal normal tissue (ab29890)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Sprouty 1 antibody - ab56670 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing HepG2 cells stained with ab56670 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab56670, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HepG2 cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-Sprouty 1 antibody - ab21020 from Abcam

Host Goat
Clonality Polyclonal

Anti-Sprouty 1 antibody [3H4] - ab117744 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3H4
Anti-Sprouty 1 antibody [3H4] (ab117744) + HepG2 cell lysate

Anti-SPRY1 / Sprouty 1 Antibody (aa1-207) - LS-C39223 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa310-319) - LS-C55526 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (N-Terminus) - LS-C126318 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa1-178) - LS-C132178 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (N-Terminus) - LS-C144694 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (N-Terminus) - LS-C153563 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa1-178, clone TS106) - LS-C191492 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TS106

Anti-SPRY1 / Sprouty 1 Antibody (aa112-303, Biotin) - LS-C301035 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa118-309, FITC) - LS-C304120 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa118-309, Biotin) - LS-C301027 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa112-303, FITC) - LS-C304126 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPRY1 / Sprouty 1 Antibody (aa35-84) - LS-C81562 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SPRY1 / Sprouty 1 Antibody (aa112-303) - LS-C296494 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SPRY1 / Sprouty 1.
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