| Gene Symbol |
SPRY1
|
| Entrez Gene |
10252
|
| Alt Symbol |
hSPRY1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
|
| Other Description |
protein sprouty homolog 1|sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling)|spry-1
|
| Swissprots |
D3DNX6 Q6PNE0 O43609
|
| Accessions |
CBX47508 CBX47509 EAX05209 EAX05210 EAX05211 O43609 AF041037 AAC39566 AK026960 AL602431 AV692593 AY192146 AAP20102 AY590694 AAT06102 BC063856 AAH63856 CA447611 CN302060 DA765300 DB250100 HQ447467 ADQ31953 XM_005262686 XP_005262743 NM_001258038 NP_001244967 NM_001258039 NP_001244968 NM_005841 NP_005832 NM_199327 NP_955359
|
| Function |
May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
|
| Subcellular Location |
Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
|
| Top Pathways |
Jak-STAT signaling pathway
|
