Gene Symbol | SPRY1 |
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Entrez Gene | 10252 |
Alt Symbol | hSPRY1 |
Species | Human |
Gene Type | protein-coding |
Description | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
Other Description | protein sprouty homolog 1|sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling)|spry-1 |
Swissprots | D3DNX6 Q6PNE0 O43609 |
Accessions | CBX47508 CBX47509 EAX05209 EAX05210 EAX05211 O43609 AF041037 AAC39566 AK026960 AL602431 AV692593 AY192146 AAP20102 AY590694 AAT06102 BC063856 AAH63856 CA447611 CN302060 DA765300 DB250100 HQ447467 ADQ31953 XM_005262686 XP_005262743 NM_001258038 NP_001244967 NM_001258039 NP_001244968 NM_005841 NP_005832 NM_199327 NP_955359 |
Function | May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor). |
Top Pathways | Jak-STAT signaling pathway |
Sprouty 1 CRISPR/Cas9 KO Plasmid (h) - sc-401299 from Santa Cruz Biotechnology
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Sprouty 1 HDR Plasmid (h) - sc-401299-HDR from Santa Cruz Biotechnology
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Sprouty 1 Double Nickase Plasmid (h) - sc-401299-NIC from Santa Cruz Biotechnology
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Sprouty 1 Double Nickase Plasmid (h2) - sc-401299-NIC-2 from Santa Cruz Biotechnology
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Sprouty 1 CRISPR Activation Plasmid (h) - sc-401299-ACT from Santa Cruz Biotechnology
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Sprouty 1 CRISPR Activation Plasmid (h2) - sc-401299-ACT-2 from Santa Cruz Biotechnology
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Sprouty 1 Lentiviral Activation Particles (h) - sc-401299-LAC from Santa Cruz Biotechnology
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Sprouty 1 Lentiviral Activation Particles (h2) - sc-401299-LAC-2 from Santa Cruz Biotechnology
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Sprouty 1 siRNA (h) - sc-41035 from Santa Cruz Biotechnology
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Sprouty 1 shRNA Plasmid (h) - sc-41035-SH from Santa Cruz Biotechnology
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Sprouty 1 shRNA (h) Lentiviral Particles - sc-41035-V from Santa Cruz Biotechnology
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SPRY1 RNAi - H00010252-R01 from Novus Biologicals
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SPRY1 RNAi - H00010252-R02 from Novus Biologicals
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MISSION® esiRNA - EHU087521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20529 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20529 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08898 from Sigma-Aldrich
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SPRY1 siRNA (Human) - CRH6939 from Cohesion Biosciences
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SPRY1 - MBS8241328 from MyBioSource
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shRNA set against Human SPRY1 (NM_005841.2) - SHH417344 from Creative biogene
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Human SPRY1 siRNA - orb267441 from Biorbyt
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SPRY1 shRNA Plasmid (Human) - CHH6939 from Cohesion Biosciences
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SPRY1 miRNA 3'UTR clone - MiUTR3H-05017 from Creative biogene
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SPRY1 miRNA 3'UTR clone - MiUTR3H-05018 from Creative biogene
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