Gene Symbol | SPRY1 |
---|---|
Entrez Gene | 10252 |
Alt Symbol | hSPRY1 |
Species | Human |
Gene Type | protein-coding |
Description | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
Other Description | protein sprouty homolog 1|sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling)|spry-1 |
Swissprots | D3DNX6 Q6PNE0 O43609 |
Accessions | CBX47508 CBX47509 EAX05209 EAX05210 EAX05211 O43609 AF041037 AAC39566 AK026960 AL602431 AV692593 AY192146 AAP20102 AY590694 AAT06102 BC063856 AAH63856 CA447611 CN302060 DA765300 DB250100 HQ447467 ADQ31953 XM_005262686 XP_005262743 NM_001258038 NP_001244967 NM_001258039 NP_001244968 NM_005841 NP_005832 NM_199327 NP_955359 |
Function | May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor). |
Top Pathways | Jak-STAT signaling pathway |